Description
Chartreusin is an antibiotic compound that also exhibits anticancer activity. Chartreusin binds GC-rich DNA sequences, inhibiting synthesis of RNA and causing free radical accumulation.
Chartreusin
Product ID C2803
Cas No. 6377-18-0
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 6377-18-0 |
|---|---|
| Purity | ≥98% |
| Formula | C32H32O14 |
| Formula Wt. | 640.6 |
| Chemical Name | Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-2-O-(6-deoxy-3-O-methyl-alpha-D- galactopyranosyl)-beta-D-galactopyranosyl)oxy)-6-hydroxy-1- methyl- (9CI) |
| IUPAC Name | 3-[(2S,3R,4S,5R,6R)-3-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4,5-dihydroxy-6-methyloxan-2-yl]oxy-8-hydroxy-15-methyl-11,18-dioxapentacyclo[10.6.2.02,7.09,19.016,20]icosa-1(19),2(7),3,5,8,12(20),13,15-octaene-10,17-dione |
| Synonym | Lambdamycin, NSC-5159. |
| Melting Point | 184-186°C |
| Solubility | Soluble in acetone. Practically insoluble in water. |
| Appearance | Yellow sold |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Blue Ice |
Downloads
| MSDS | |
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| Info Sheet |
References
Portugal J. Chartreusin, elsamicin A and related anti-cancer antibiotics. Curr Med Chem Anticancer Agents. 2003 Nov;3(6):411-20. PMID: 14529449.
Uramoto M, Kusano T, Nishio T, et al. Specific binding of chartreusin, an antitumor antibiotic, to DNA. FEBS Lett. 1983 Mar 21;153(2):325-8. PMID: 6311618.
Yagi M, Nishimura T, Suzuki H, et al. Chartreusin, an antitumor glycoside antibiotic, induces DNA strand scission. Biochem Biophys Res Commun. 1981 Feb 12;98(3):642-7. PMID: 7225117.