LKT Labs

Biochemicals for Life Science Research

Urocortin, human

Urocortin, human

Product ID U6854
Cas No. 171543-83-2
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $408.90 In stock
1 mg $694.90 Please Inquire
2.5 mg $1,226.60 Please Inquire
Bulk Quote

Quicklinks

Description

Urocortin is an endogenous peptide ligand and member of the corticotropin-releasing factor (CRF) family; it binds and activates CRF type 1 and 2 receptors. Urocortin modulates stress responses and exhibits anorexigenic, anxiogenic, and positive inotropic effects across a wide variety of in vivo models. Urocortin is primarily expressed in the heart. Urocortin exerts many effects on signaling of the hypothalamic-pituitary-adrenal (HPA) axis, including increasing corticosterone and adrenocorticotropic hormone (corticotropin) levels.

Product Info

Cas No.

171543-83-2
Purity

≥98%
Formula

C204H337N63O64
Formula Wt.

4696.3
Solubility

Soluble in water (1 mg/mL).

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

U6854 MSDS PDF
Info Sheet

U6854 Info Sheet PDF

References

Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • K0054

    Kanamycin B

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • D3429

    Dihydrocytochalasin B

    Mycotoxin derivative; actin polymerization inhi...

    ≥98%
  • T1644

    Telmisartan

    AT-II antagonist, PPARγ/δ modulator.

    ≥98%
  • C344761

    Citalopram Chloromethyl Quaternary Ammonium Chloride

    Citalopram analog

    ≥95%
  • X4402

    XL-147

    Dual inhibitor of PI3K and mTOR.

    ≥98%
  • N1769

    Nerolidol, synthetic

    AChE inhibitor, F0F1-ATP synthase modulator.

    A mixture of cis and trans isomers, ≥96%
  • A6823

    Argatroban

    Thrombin inhibitor.

    ≥98%
  • M1649

    Melanoma-associated Antigen Peptide 1 (27-35), human

    Melanoma-associated antigen.

    ≥95%
  • C0171

    Carboplatin

    Pt-based DNA cross-linker.

    ≥99%
  • B6957

    Bromhexine Hydrochloride

    Synthetic derivative of vasicine, mucolytic.

    ≥98%
  • M5756

    Montelukast Sodium

    CysLT1 antagonist.

    ≥98%
  • F4556

    Florfenicol

    Synthetic fluorinated thiamphenicol analog; pro...

    ≥98%
  • D3431

    3,4-Dihydroxyphenyl Ethanol

    Polyphenol found in olive oil, antioxidant.

    ≥95%
  • P5745

    Polygalic Acid

    Saponin found in Polygala.

    ≥97%
  • F5871

    N-formyl-Met-Leu-Phe-Lys

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • D324094

    Diclofenac Related Compound A

    Impurity of diclofenac

    ≥98%
  • Z0222

    Zafirlukast

    VEGF-C/Nrp2 inhibitor. Leukotriene receptor ant...

    ≥98%
  • D183734

    7-O-Desmethyl Rapamycin

    Rapamycin impurity

    ≥85%
  • O4556

    Olomoucine

    Purine derivative; CDK inhibitor.

    ≥98%
  • Z161022

    α-Zearalanol

    Mycotoxin that has structural similarity to est...

    ≥98%