Description
This naphthalene exhibits anticancer activity; in fibrosarcoma and breast cancer cells, it increases expression of STAT1 and IFN regulatory factor 1 and enhances the ability of IFNγ to inhibit cell proliferation.
2-(1,8-Naphthyridin-2-yl)phenol
Product ID N0163
Cas No. 65182-56-1
Purity ≥98%
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Product Info
| Cas No. | 65182-56-1 |
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| Purity | ≥98% |
| Formula | C14H10N2O |
| Formula Wt. | 222.24 |
| IUPAC Name | 6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one |
| Synonym | 2-NP |
| Solubility | Ethanol (7 mg/mL), DMSO (50 mg/mL) |
| Appearance | Red Crystals |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Lynch RA, Etchin J, Battle TE, et al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61. PMID: 17283162.