Description
Beclomethasone Dipropionate is a corticosteroid anti-inflammatory and vasoconstrictive agent. This prodrug undergoes hydrolysis to give the active monoester 17-beclomethasone monopropionate, which binds to the glucocorticoid receptor.
Beclomethasone Dipropionate
Product ID B164094
Cas No. 5534-09-8
Purity ≥99%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 5534-09-8 |
|---|---|
| Purity | ≥99% |
| Formula | C28H37ClO7 |
| Formula Wt. | 521.0 |
| Chemical Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate |
| IUPAC Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate |
| Synonym | Beclometasone dipropionate; Beclovent; Beconase |
| Appearance | White to off white crystal powder |
Shipping and Storage
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Fugazzola M, Barton A, Niedorf F, et al. Non-genomic action of beclomethasone dipropionate on bronchoconstriction caused by leukotriene C4 in precision cut lung slices in the horse. BMC Vet Res. 2012 Sep 10;8:160. PMID: 22963524.
Wu H, Chuang Y, Lin H, et al. Immediate release formulation of inhaled beclomethasone dipropionate-hydroxypropyl-beta-cyclodextrin composite particles produced using supercritical assisted atomization. Polymers (Basel). 2022 May 23;14(10):2114. PMID: 35631996.
Usmani S, Baldi S, Warren E, et al. Lung deposition of inhaled extrafine beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide in healthy volunteers and asthma: the STORM study. J Aerosol Med Pulm Drug Deliv. 2022 Aug;35(4):179-185. PMID: 35128939.
Casula L, Lai F, Pini E, et al. Pulmonary delivery of curcumin and beclomethasone dipropionate in a multicomponent nanosuspension for the treatment of bronchial asthma. Pharmaceutics. 2021 Aug 20;13(8):1300. PMID: 34452261.