Description
Cridanimod is a STING agonist in mouse cells but not human cells.9-Oxo-10(9H)-acridineacetic acid (CAS 38609-97-1)
Cridanimod
Product ID C691325
Cas No. 38609-97-1
Purity ≥99%
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Product Info
| Cas No. | 38609-97-1 |
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| Purity | ≥99% |
| Formula | C15H11NO3 |
| Formula Wt. | 253.26 |
| Chemical Name | 2-(9-oxoacridin-10-yl)acetic acid |
| IUPAC Name | 2-(9-oxoacridin-10-yl)acetic acid |
| Synonym | 10-carboxymethyl-9-acridanone; CMA; 9-Oxo-10(9H)-acridineacetic acid; 9-Oxoacridine-10-acetic acid |
| Melting Point | 286.4°C ~ 286.7°C |
| Solubility | Insoluble in water. DMSO (≥100 mg/m). |
| Appearance | Yellow to yellowish green crystalline powder |
Shipping and Storage
| Store Temp | 4°C |
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| Ship Temp | Ambient |
Downloads
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References
Keyer V, Syzdykova L, Zauatbayeva G, et al. Tilorone and cridanimod protect mice and show antiviral activity in rats despite absence of the interferon-inducing effect in rats. Pharmaceuticals (Basel).2022 May 17;15(5):617. PMID: 35631443
Ding C, Song Z, Shen A, et al. Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway. Acta Pharm Sin B. 2020 Dec;10(12):2272-2298. PMID: 33354501
Cavlar T, Deimling T, Ablasser A, et al. Species-specific detection of the antiviral small-molecule compound CMA by STING. EMBO J. 2013 May 15;32(10):1440-1450. PMID: 23604073