Description
STING Agonist-12 is an activator of STING.
STING Agonist-12
Product ID S771339
Cas No. 2259624-71-8
Purity ≥99%
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Product Info
| Cas No. | 2259624-71-8 |
|---|---|
| Purity | ≥99% |
| Formula | C25H19ClF4N2O2 |
| Formula Wt. | 490.88 |
| IUPAC Name | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]indole-6-carboxamide |
| Synonym | Compound 53, STING Agonist C53, GTPL11960 |
| Appearance | White powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Pryde D, Middya S, Banerjee M, et al. The discovery of potent small molecule activators of human STING. Eur J Med Chem. 2021 Jan 1;209:112869. PMID: 33038794
Lu D, Shang G, Li J, et al. Activation of STING by targeting a pocket in the transmembrane domain. Nature. 2022 Apr;604(7906):557-562. PMID: 35388221