| Product Unit Size | Cost | Quantity | Stock |
|---|
Ritodrine is a β2-adrenergic receptor agonist that exhibits tocolytic activity. Ritodrine is clinically used to prevent preterm labor, as it decreases prostanoid signaling and inhibits uterine contractility. Ritodrine activates Ca2+-activated (SK/BK) K+ channels and ATP-sensitive K+ channels, potentially underlying its smooth muscle cell relaxant effects. Additionally, ritodrine may induce the formation of pruritic erythematous papular eruptions when used clinically.
| Cas No. | 23239-51-2 |
|---|---|
| Purity | ≥98% |
| Formula | C17H21NO3 • HCl |
| Formula Wt. | 323.82 |
| IUPAC Name | 4-[2-[[(1R, 2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenol; hydrochloride |
| Synonym | Ritodrina, Ritodrinium |
| Melting Point | 192-196°C |
| Appearance | White to Yellow Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sato Y, Teraki Y, Izaki S, et al. Ritodrine-induced erythematous papular eruption in 14 pregnant women. Int J Dermatol. 2010 Dec;49(12):1450-3. PMID: 21091685.
Schwarz MK, Page P. Preterm labour: an overview of current and emerging therapeutics. Curr Med Chem. 2003 Aug;10(15):1441-68. PMID: 12871140.
Hamada Y, Nakaya Y, Hamada S, et al. Activation of K+ channels by ritodrine hydrochloride in uterine smooth muscle cells from pregnant women. Eur J Pharmacol. 1994 Dec 15;288(1):45-51. PMID: 7705467.
Dubin NH, Ghodgaonkar RB. Effect of ritodrine hydrochloride and dibutyryl cyclic AMP on contractile activity and prostanoid production of uteri from pregnant rats in vitro. Prostaglandins Leukot Med. 1984 Feb;13(2):119-28. PMID: 6326162.