Alternariol-9-methyl Ether

Name: Alternariol-9-methyl Ether
SKU: A4678
Availability: InStock

Product ID A4678

Cas No. 26894-49-5; 23452-05-3

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Alternariol 9-methyl ether (A9ME) is a highly toxic mutagenic phytotoxin initially produced by species of Alternaria. A9ME is present in grain and fruit used for livestock feed and human consumption. A9ME inhibits the electron transport chain, preventing photosynthesis in vitro. Additionally, A9ME may exhibit anticancer potential in a cellular model of colon carcinoma, as it decreases the mitochondrial membrane potential, increasing release of cytochrome c and activating caspases 3 and 9; this results in apoptosis and cell death.

Product Info

Cas No.	26894-49-5; 23452-05-3
Purity	≥98%
Formula	C₁₅H₁₂O₅
Formula Wt.	272.25
Chemical Name	6H-Dibenzo(b,d)pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl
IUPAC Name	3,7-dihydroxy-9-methoxy-1-methylbenzo[c]chromen-6-one
Synonym	AME; Djalonensone; Alternariol monomethyl ether; Alternariol methyl ether; Alternariol-9-methyl ether
Solubility	Soluble in DMSO, ethanol, methanol
Appearance	Beige Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	A4678 MSDS PDF
Info Sheet	A4678 Info Sheet PDF

References

Demuner AJ, Barbosa LC, Miranda AC, et al. The Fungal Phytotoxin Alternariol 9-Methyl Ether and Some of Its Synthetic Analogues Inhibit the Photosynthetic Electron Transport Chain. J Nat Prod. 2013 Nov 18. [Epub ahead of print]. PMID: 24245962.

Broggi L, Reynoso C, Resnik S, et al. Occurrence of alternariol and alternariol monomethyl ether in beverages from the Entre Rios Province market, Argentina. Mycotoxin Res. 2013 Feb;29(1):17-22. PMID: 23334721.

Scott PM, Zhao W, Feng S, et al. Alternaria toxins alternariol and alternariol monomethyl ether in grain foods in Canada. Mycotoxin Res. 2012 Nov;28(4):261-6. PMID: 23087499.

Bensassi F, Gallerne C, el Dein OS, et al. Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells. Toxicology. 2011 Dec 18;290(2-3):230-40. PMID: 22001388.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Phone
This field is for validation purposes and should be left unchanged.

Alternariol-9-methyl Ether

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Urocortin II, human

[Lys8]-Vasopressin

Aflatoxin M2

Rosiglitazone

Silodosin

JZL184

Podophyllotoxin

Nicardipine

Betulinic Acid

Coelenterazine, natural

CYT-387

Azacitidine

Rifampicin

Psoralidin

Raloxifene Hydrochloride

Carbenoxolone

Taxinin M

Brefeldin A

Cefuroxime Sodium

Vandetanib

Footer