Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Product Unit Size | Cost | Quantity | Stock |
---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Cas No. | 1246560-33-7 |
---|---|
Purity | ≥98% |
Formula | C17H22N8O |
Formula Wt. | 354.41 |
IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
Synonym | SB2343, SB-2343, VS5584 |
Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
Antimicrobial peptide found in frogs, induces p...
p110α and p110γ PI3K inhibitor.
Endogenous neuropeptide hormone; somatostatin a...
ROCK inhibitor.
STING inhibitor
Opioid neuropeptide; kyotorphin agonist.
Endogenous hormone and neurotransmitter involve...
Sulfonylurea; SUR1 antagonist.
mAChR antaonist.
Peptide produced in tomato leaves; potential ca...
Laminin-derived peptapeptide.
Alkaloid compound originally found in Corydalis...
Endogenous peptide, involved in immune signalin...
Flavonolignan mixture found in Silybum (milk th...
mTOR inhibitor.
Diterpene alkaloid found in Lagochilus.
Arylbenzimidazole; CHK2 inhibitor.
Flavonol glycoside originally found in Epimediu...
Vitamin D prodrug produced by fungi and alfalfa...
Mycotoxin produced by Penicillum and Aspergillu...