Description
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Product Unit Size | Cost | Quantity | Stock |
---|
VS-5584 inhibits PI3K and displays anticancer chemotherapeutic activity, inhibiting cell proliferation in a variety of cancer cell lines and suppressing tumor growth in animal models of gastric cancer.
Cas No. | 1246560-33-7 |
---|---|
Purity | ≥98% |
Formula | C17H22N8O |
Formula Wt. | 354.41 |
IUPAC Name | 5-(8-methyl-2-morpholin-4-yl-9-propan-2-ylpurin-6-yl)pyrimidin-2-amine |
Synonym | SB2343, SB-2343, VS5584 |
Solubility | DMSO 71 mg/mL (200.33 mM) Ethanol 3 mg/mL (8.46 mM) Water Insoluble |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013 Feb;12(2):151-61. PMID: 23270925.
Statin, naturally produced by mushrooms; HMG-Co...
Polyketide; DNMT 1 inhibitor, RNA synthesis inh...
Diterpene found in coffee beans.
Protein translation inhibitor, peptidyl transfe...
Endogenous peptide hormone, GLP-1 fragment, inv...
Semi-synthetic derivative of chlorophyll; food ...
AChE inhibitor.
Epipodophyllotoxin derivative; topoisomerase II...
Diterpene found in Taxus; potential microtubule...
Chalcone; SIRT activator, GABA-A positive modul...
Nucleoside (thymidine) analog; DNA chain termin...
Coccidiostat.
MGMT inhibitor.
Degrades of BET proteins.
Steroid; glucocorticoid agonist.
Lignin found in Sesamin indicum;
Aromatase inhibitor.
p110α PI3K inhibitor.
Triazole; 14α demethylase inhibitor.
2-methyl-1,4-naphthoquinone derivative