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β-Carotene

β-Carotene

Product ID C0269
Cas No. 7235-40-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $30.70 In stock
5 g $61.10 In stock
25 g $204.30 In stock
50 g $347.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

β-Carotene is a red-orange terpene pigment originally found in various plants and fruits; it is a prodrug for vitamin A. β-Carotene exhibits antioxidative, cytoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. β-Carotene is used in research models to quantify antioxidative activity. In bone marrow cells, β-carotene protects against radioactive isotope-induced DNA damage. In breast cancer cells, this compound induces cell cycle arrest and apoptosis, decreasing cellular viability. β-Carotene decreases total cholesterol, VLDL and LDL levels, suppresses expression of SREBP2 and LDL-R, and increases expression of PPARα in vivo. In other animal models, this compound decreases body fat and adipocyte size and suppresses TNF-α-induced inflammation.

Product Info

Cas No.

7235-40-7

Purity

≥98%

Formula

C40H56

Formula Wt.

536.87

Chemical Name

β,β-Carotene

IUPAC Name

1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12, 16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11, 13,15,17-nonaenyl]cyclohexene

Synonym

Carotaben, Provatene, Solatene

Melting Point

183°C

Solubility

Insoluble in water. Sparingly soluble in ethanol. Soluble in benzene or chloroform.

Appearance

Dark Yellowish Red Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C0269 MSDS PDF

Info Sheet

C0269 Info Sheet PDF

References

Abdel-Mageed WM, Bayoumi SA, Salama AA, et al. Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pac J Trop Med. 2014 Sep;7S1:S521-6. PMID: 25312177.

Berti AP, Düsman E, Mariucci RG, et al. Antimutagenic and radioprotective activities of beta-carotene against the biological effects of iodine-131 radiopharmaceutical in Wistar rats. Genet Mol Res. 2014 Mar 31;13(1):2248-58. PMID: 24737473.

Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385.

Silva LS, de Miranda AM, de Brito Magalhães CL, et al. Diet supplementation with beta-carotene improves the serum lipid profile in rats fed a cholesterol-enriched diet. J Physiol Biochem. 2013 Dec;69(4):811-20. PMID: 23645541.

Di Tomo P, Canali R, Ciavardelli D, et al. β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes. Mol Nutr Food Res. 2012 Feb;56(2):217-27. PMID: 22162208.

Amengual J, Gouranton E, van Helden YG, et al. Beta-carotene reduces body adiposity of mice via BCMO1. PLoS One. 2011;6(6):e20644. PMID: 21673813.

Custom Order

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