• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
(−)-Bilobalide

(−)-Bilobalide

Product ID B3345
Cas No. 33570-04-6
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $71.50 In stock
10 mg $128.50 In stock
25 mg $296.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bilobalide is a sesquiterpene lactone found in Ginkgo that exhibits neuroprotective, cognition enhancing, anxiolytic, antioxidative, anti-inflammatory, and analgesic activities. Bilobalide inhibits GABA-A receptors, decreases anxiety, and improves spatial learning and memory in vivo. In animal models of cerebral ischemia/reperfusion, bilobalide decreases edema and infarct volume. In adipocytes, this compound inhibits hypoxia-induced oxidative stress and inflammation. Additionally, bilobalide inhibits carrageenan- and capsaicin-induced hyperalgesia in animal models.

Product Info

Cas No.

33570-04-6

Purity

≥98%

Formula

C15H18O8

Formula Wt.

326.30

Chemical Name

(5aR-(3aS,5aα,8b,8aS,9a,10aα))-9-(1,1-dimethylethyl)- 10,10a-dihydro-8,9-dihydroxy-4H,5aH,9H-furo[2,3-b]furo[3',2':2,3]cyclopenta[1,2-c]furan-2,4,7(3H,8H)- trione

IUPAC Name

(1S,4R,7R,8S,9R,11S)-9-tert-butyl-7,9-dihydroxy-3,5,12-trioxatetracyclo[6.6.0.01,11.04,8]tetradecane-2,6,13-trione

Synonym

Bilobalide

Melting Point

300°C

Solubility

Soluble in ethanol or DMSO.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B3345 MSDS PDF

Info Sheet

B3345 Info Sheet PDF

References

A P, V M N, S S A, et al. Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3 L1 adipocytes via its antioxidant potential. Free Radic Res. 2014 Jul 21:1-31. PMID: 25039303.

Goldie M, Dolan S. Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats. Behav Pharmacol. 2013 Aug;24(4):298-306. PMID: 23838965.

Ma L, Wang S, Tai F, et al. Effects of bilobalide on anxiety, spatial learning, memory and levels of hippocampal glucocorticoid receptors in male Kunming mice. Phytomedicine. 2012 Dec 15;20(1):89-96. PMID: 23083816.

Defeudis FV. Bilobalide and neuroprotection. Pharmacol Res. 2002 Dec;46(6):565-8. PMID: 12457632.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • T0106

    Xylosyltaxol

    Taxane found in species of Taxus; potential mic...

    ≥98%
  • O4532

    Oligomycin B

    Macrolide; F1F0 ATP synthase inhibitor.

    ≥97%, TLC, HPLC
  • E5217

    β-Endorphin, human

    Endogenous opioid peptide; μOR agonist.

    ≥95%
  • I4659

    Iloperidone

    Benzisoxazole phenylethanone; D2 and 5-HT2A ant...

    ≥99%
  • P1969

    Perifosine

    Alkylphospholipid analog; Akt inhibitor.

    ≥98%
  • N8277

    Nutlin-3

    Imidzoline derivative; MDM2 inhibitor.

    ≥95%
  • F4780

    Fluoxetine Hydrochloride

    FIASMA, SERT inhibitor, 5-HT and σ1 antagonist...

    ≥98%
  • M3344

    Milrinone

    PDE3 inhibitor.

    ≥98%
  • E6134

    Epimedin C

    Flavonoid found in Epimedium sagittatum.

    ≥98%
  • L8377

    Luteolin

    Flavonoid found in various plant sources; DAT a...

    ≥95%
  • R0109

    Racecadotril

    Enkephalinase inhibitor.

    ≥98%
  • D178589

    1-Deoxynojirimycin

    Anti-diabetic alkaloid

    ≥98%
  • R327201

    Rifapentine

    Antibiotic

    ≥97%
  • C000082

    C-82

    beta-catenin inhibitor

    ≥99%
  • O0400

    Obatoclax

    BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.

    ≥98%
  • G0244

    alpha-Galactosylceramide

    Synthetic glycolipid found in Agelas mauritaniu...

    ≥96%
  • T503720

    TMS

    Selective inhibitor of cytochrome P450 1B1 (CYP...

    ≥99%
  • A5134

    Aminophylline Anhydrous

    Adenosine antagonist, PDE inhibitor.

    ≥98%
  • A7604

    ATB 346

    NSAID; COX inhibitor and HS-releasing agent.

    ≥99%
  • Z5744

    Zoledronic Acid Hydrate

    Bisphosphonate; FPPS inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only