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10-Acetoacetyl Paclitaxel

10-Acetoacetyl Paclitaxel

Product ID T1006
Cas No.
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $708.60 In stock
5 mg $2,589.20 In stock
10 mg $4,360.90 In stock
25 mg $8,721.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

10-Acetoacetyl Paclitaxel is an impurity of the chemotherapy drug paclitaxel.

Product Info

Purity

≥95%

Formula

C49H53NO15

Formula Wt.

895.94

Chemical Name

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3R)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-6-((3-oxobutanoyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

Synonym

Paclitaxel, acetoacetyl; 10-Acetoacetyl Abraxane; 10-Acetoacetyl Genaxol; 10-Acetoacetyl Genetaxyl; 10-Acetoacetyl Onxal; 10-Acetoacetyl Pacliex; 10-Acetoacetyl (-)-Paclitaxel; 10-Acetoacetyl Taxol

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

T1006 MSDS PDF

Info Sheet

T1006 Info Sheet PDF

References

Nicolaou K, Yang Z, Liu J, et al. Total synthesis of taxol. Nature. 1994 Feb 17;367(6464):630-634. PMID: 7906395.

Nicolaou K, Valiulin R. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 7;11(25):4154-4163. PMID: 23685867.

Sanchez-Munoz R, Perez-Mata E, Almagro L, et al. A novel hydroxylation step in the taxane biosynthetic pathway: a new approach to paclitaxel production by synthetic biology. Front Bioeng Biotechnol. 2020 May 13;8::410. PMID: 32528936.

Guo B, Kai G, Jin H, et al. Taxol synthesis. African J Biotechnol. 2006 Jan 2;5(1):15-20.

Wang T, Chen Y, Zhuang W, et al. Transcriptome sequencing reveals regulatory mechanisms of taxol synthesis in Taxus wallichiana var. Mairei. Int J Genomics. 2019 May 2;2019:1596895. PMID: 31192250.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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