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Zalcitabine, also known as 2’,3’-dideoxycytidine, is an antiviral pyrimidine nucleoside analog that is clinically used to treat HIV infection. Zalcitabine inhibits reverse transcriptase and prevents chain elongation when incorporated into viral DNA.
| Cas No. | 7481-89-2 |
|---|---|
| Purity | ≥98% |
| Formula | C9H13N3O3 |
| Formula Wt. | 211.22 |
| IUPAC Name | 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| Synonym | Zalcitabine, ddCyd, Hivid |
| Melting Point | 215-217°C |
| Solubility | Slightly soluble in water, DMSO, methanol. |
| Appearance | White crystal Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet | |
| Brochures |
Shelton MJ, O'Donnell AM, Morse GD. Zalcitabine. Ann Pharmacother. 1993 Apr;27(4):480-9. PMID: 8097417.
Balzarini J. Anti-retroviral activity and molecular-biochemical action mechanism of 2',3'-dideoxynucleoside analogs and 9-(2-phosphonylmethoxyethyl) purine derivatives. Verh K Acad Geneeskd Belg. 1991;53(1):61-98. PMID: 1647085.