• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Cytochalasin D

Cytochalasin D

Product ID C9881
Cas No. 22144-77-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $236.40 In stock
5 mg $976.60 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cytochalasin D is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin D exhibits anti-angiogenic and pro-oxidative activities. In endothelial cells, cytochalasin D inhibits FGF- and VEGF-induced angiogenesis. In other cellular models, cytochalasin D increases production of ROS and activity of NADPH oxidase. Additionally, this compound increases levels of PPARγ, lipoprotein lipase, and FABP4, controlling adipogenesis in stem cells through its effects on cytoskeletal tension.

Product Info

Cas No.

22144-77-0

Purity

≥98%

Formula

C30H37NO6

Formula Wt.

507.62

IUPAC Name

[(1R,2R,3E,5R,7S,9E,11R,12S,14S,15R,16S)-16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate

Melting Point

255°C (dec)

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C9881 MSDS PDF

Info Sheet

C9881 Info Sheet PDF

References

Wilkins JR, Pike DB, Gibson CC, et al. Differential effects of cyclic stretch on bFGF- and VEGF-induced sprouting angiogenesis. Biotechnol Prog. 2014 Feb 14. [Epub ahead of print]. PMID: 24574264.

Choy JS, Lu X, Yang J, et al. Endothelial actin depolymerization mediates NADPH oxidase-superoxide production during flow reversal. Am J Physiol Heart Circ Physiol. 2014 Jan 1;306(1):H69-77. PMID: 24186098.

Schiller ZA, Schiele NR, Sims JK, et al. Adipogenesis of adipose-derived stem cells may be regulated via the cytoskeleton at physiological oxygen levels in vitro. Stem Cell Res Ther. 2013 Jul 9;4(4):79. PMID: 23838354.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P4132

    PKI-402

    p110α PI3K and mTOR inhibitor.

    ≥98%
  • N344780

    N-Nitroso Bumetanide

    Bumetanide impurity

    ≥99%
  • R1779

    13-cis-Retinoic Acid

    Vitamin A metabolite, differentiation inducer; ...

    97%
  • B0397

    BAY80-6946 Hydrochloride

    pan-PI3K inhibitor

    ≥98%
  • O486188

    Omeprazole Impurity F and G mixture

    Regioisomers

    ≥98%
  • L337521

    Linagliptin

    Modifies microvascular function

    ≥98%
  • T3038

    Thienylnonanyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • R5722

    Rofecoxib

    NSAID; COX-2 inhibitor.

    ≥98%
  • D3348

    11,12-Dimethoxydihydrokawain

    Kawain derivative, lactone found in Piper methy...

    ≥97%
  • B1652

    Benzo[a]pyrene

    Polycyclic aromatic hydrocarbon (PAH) found in ...

    ≥98%
  • M185770

    5-Methyltetrahydrofolic Acid

    Folic acid derivative

    ≥98%
  • A7618

    Atenolol

    β1-adrenergic antagonist.

    ≥98%
  • P2845

    Phleomycin

    Glycopeptide, metal ion chelator, induces DNA s...

    ≥97%
  • V014451

    Valiltramiprosate

    beta-Amyloid anti-oligomer and aggregation inhi...

    ≥99%
  • P4782

    PluriSIn 1

    Stearoyl-coA desaturase 1 inhibitor.

    ≥98%
  • U0618

    Ubenimex

    Dipeptide; aminopeptidase (N/CD13) inhibitor.

    ≥98%
  • G3455

    Ginsenoside Rc

    Triterpene saponin found in species of Panax; A...

    ≥98%
  • Y4800

    YM-155

    Survivin inhibitor.

    ≥99%
  • C0174

    Carmofur

    Pyrimidine analog, fluorouracil derivative; thy...

    ≥97%
  • U6873

    Ursodeoxycholic Acid

    Endogenous secondary bile acid.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only