Description
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
Product Unit Size | Cost | Quantity | Stock |
---|
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
Cas No. | 63597-44-4 |
---|---|
Purity | ≥98% |
Formula | C36H56O8 |
Formula Wt. | 616.83 |
Chemical Name | 4-α-12-Tetradecanoyl phorbol-13-acetate |
IUPAC Name | [(1S,2S,6S,10S,11R,13S,14R,15R)-13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] tetradecanoate |
Synonym | 4-αPMA |
Solubility | Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. |
Appearance | White to off white powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Chahine M, Qu Y, Mancarella S, et al. Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis. Pflugers Arch. 2008 Feb;455(5):913-9. PMID: 17909852.
Tosco M, Orsenigo MN, Gastaldi G, et al. Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. Exp Physiol. 2002 Nov;87(6):653-62. PMID: 12530398.
Quinoid diterpene found in species of Salvia; S...
Endogenous peptide, involved in stress signalin...
Shellfish toxin produced by dinoflagellates and...
Non-alkaloid lignan found in Podophyllum,deriva...
Trihydroxybenzoic acid glycoside found in Berge...
Coumarin lactone found in chicory and other pla...
Primarily targets HDAC1
Thienopyridine; P2Y12 antagonist.
Caspase 3 substrate.
Polyketide; DNMT 1 inhibitor, RNA synthesis inh...
CHK1 inhibitor.
Tropane alkaloid found in Solanaceae plants; mA...
c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5...
5-HT3 antagonist.
Sesquiterpene lactone found in Artemisia (wormw...
Found in Cephalosporium; fatty acid synthase in...
Selective inhibitor of c-Met.
Endogenous steroid hormone involved in stress s...
Anti-diabetic alkaloid