Description
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
| Product Unit Size | Cost | Quantity | Stock |
|---|
4-α-Phorbol-12-myristate-13-acetate (4-α-PMA) is an inactive compound used as a negative control in research models examining activation of PKC and other effects by PMA.
| Cas No. | 63597-44-4 |
|---|---|
| Purity | ≥98% |
| Formula | C36H56O8 |
| Formula Wt. | 616.83 |
| Chemical Name | 4-α-12-Tetradecanoyl phorbol-13-acetate |
| IUPAC Name | [(1S,2S,6S,10S,11R,13S,14R,15R)-13-acetyloxy-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] tetradecanoate |
| Synonym | 4-αPMA |
| Solubility | Soluble in DMSO, methanol, ethanol, ethyl acetate, or chloroform. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Chahine M, Qu Y, Mancarella S, et al. Protein kinase C activation inhibits alpha1D L-type Ca channel: a single-channel analysis. Pflugers Arch. 2008 Feb;455(5):913-9. PMID: 17909852.
Tosco M, Orsenigo MN, Gastaldi G, et al. Protein kinase C regulation of rat jejunal transport system: mechanisms involved in lactate movement. Exp Physiol. 2002 Nov;87(6):653-62. PMID: 12530398.
BHA derivative, antioxidative food and cosmetic...
Synthetic steroid hormone used in HRT; SERM, PR...
Synthetic ghrelin analog; ghrelin agonist.
Peptide, fibrinogen E analog found in Amaranthu...
FIASMA, 5-HT3 and σ1 agonist, SERT inhibitor.<...
Endogenous neuropeptide hormone, involved in so...
Quaternary ammonium cationic surfactant, dissoc...
Pyrimidine analog, fluorouracil derivative; thy...
Anti-tuberculosis
Semi-synthetic avermectin; GABA potentiator.
Peptide, involved in neutrophil activation; FPR...
Melatonin analog; MT1/2 agonist, 5-HT2C antagon...
NSAID; COX-1/2 inhibitor.
NO donor; annexin A2 inhibitor.
Endogenous alkaloid also found in citrus fruits...
Non-depolarizing NMJ blocker; nAChR antagonist....
Inhibitor of EGFR.
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
β2-adrenergic agonist.
Lincosamide; peptidyl transferase inhibitor, pr...