A-803467 is a blocker of Nav1.8 (SCN10A) Na+ channels that exhibits antinociceptive and antiarrhythmic activities; it may also block Nav1.5 (SCN5A) Na+ channels. A-803467 inhibits mechanical and thermal pain nociception in vivo. This compound also blocks cardiac Na+ currents and alters action potential morphology in ventricular myocytes.
| Cas No. | 944261-79-4 |
|---|---|
| Purity | ≥98% |
| Formula | C19H16ClNO4 |
| Formula Wt. | 357.79 |
| IUPAC Name | 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furamide |
| Solubility | DMSO 72 mg/mL Ethanol 11 mg/mL Water Insoluble |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
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