• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
A23187 Ca-Mg

A23187 Ca-Mg

Product ID A0102
Cas No.
Purity ≥98%, TLC
Product Unit SizeCostQuantityStock
5 mg $152.40 In stock
10 mg $281.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

A23187 is a Ca2+ ionophore that exhibits pro-inflammatory and allergic activities. In cardiomyocytes, A23187 induces formation of endothelial microvesicles, increasing leakage of lactate dehydrogenase and decreasing cell viability. A23187 also induces mast cell degranulation and increases production of TNF-α. In spermatozoa, this compound induces the acrosome reaction, allowing fertilization to occur in the absence of PKA activation.

Product Info

Purity

≥98%, TLC

Formula

(C29H36N3O6)2Mg • (C29H36N3O6)2Ca

Formula Wt.

523.62

Synonym

Calcium-magnesium salt of A23187, Calcium-magnesium salt of calcimycin.

Melting Point

230°-250°C. (dec)

Solubility

Insoluble in water, hexane. Slightly soluble in ethanol, methanol. Soluble in choloform, acetone.

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A0102 MSDS PDF

Info Sheet

A0102 Info Sheet PDF

References

Kim DY, Kang TB, Shim DW, et al. Emodin attenuates A23187-induced mast cell degranulation and tumor necrosis factor-α secretion through protein kinase C and IκB kinase 2 signaling. Eur J Pharmacol. 2014 Jan 15;723:501-6. PMID: 24239713.

Shang M, Zhang Q, Zhang MX, et al. Effects of endothelial microvesicles induced by A23187 on H9c2 cardiomyocytes. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2013 Nov;29(6):559-64. PMID: 24654540.

Tateno H, Krapf D, Hino T, et al. Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. PMID: 24128762.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C9608

    Cycloastragenol

    Triterpene aglycone found in Radix Astragali; t...

    ≥98%
  • B5753

    Bongkrekic Acid

    Respiratory toxin, mitochondrial permeability t...

    ≥95%
  • P2012

    PF-04217903

    Triazolopyrazine; c-MET inhibitor.

    ≥98%
  • A4002

    AK-7

    SIRT2 inhibitor.

    ≥98%
  • J5237

    JNJ-26854165

    MDM2 inhibitor.

    ≥98%
  • C0253

    Candesartan

    AT1 inhibitor.

    ≥98%
  • X1854

    p-Xyleneselenocyanate

    Synthetic derivative of selenocyanate.

    ≥99%
  • C2960

    Chondroitin Sulfate, cow

    Polyanionic sulfated glycosaminoglycan, encogen...

    ≥90%
  • L1785

    Levofloxacin Hemihydrate

    Fluoroquinolone, S-(-) isomer of ofloxacin; top...

    ≥98%
  • I1257

    Idoxuridine

    Nucleoside (deoxyuridine) analog; DNA chain ter...

    ≥98%
  • O7053

    L-Ornithine Hydrochloride

    Non-proteinogenic amino acid, L-arginine metabo...

    ≥98%
  • T0004

    T2 toxin Triol

    Trichothecene mycotoxin produced by Fusarium; p...

    ≥97%, TLC
  • K6276

    (E)-KPT-330

    CRM1-selective inhibitor of nuclear export.

    ≥99%
  • E7356

    Esomeprazole Magnesium Trihydrate

    S-isomer of omeprazole; H+/K+ ATPase inhibitor....

    ≥99%
  • S8047

    R,S-Sulforaphane, Research Grade

    Synthetic ITC.

    ≥97%
  • S0225

    SAG Dihydrochloride

    Smoothened agonist.

    ≥98%
  • M1575

    7-Methyl-6-mercaptopurine

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥87%
  • D0032

    Daidzein

    Phytoestrogen, isoflavone found in various plan...

    ≥97%
  • C2468

    β-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥98%
  • L0226

    Lagochiline

    Diterpene alkaloid found in Lagochilus.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only