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Capsanthin

Product ID C0260
Cas No. 465-42-9
Purity Color value:100
Product Unit SizeCostQuantityStock
10 g $102.10 Please Inquire
50 g $179.50 In stock
100 g $280.80 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Capsanthin is a carotenoid originally found in Capsicum that exhibits anticancer and chemopreventive activities. In leukemia cells, capsanthin upregulates expression of PPARγ, Nrf2, and p21, downregulates expression of cyclin D1, induces apoptosis, and inhibits cellular proliferation. In animal models, this compound increases levels of HDL and upregulates expression of ApoA5 and LCAT. Additionally, capsanthin inhibits TPA-induced tumor development in vitro and in vivo.

Product Info

Cas No.

465-42-9

Purity

Color value:100

Formula

C40H56O3

Formula Wt.

584.87

IUPAC Name

(2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-hydroxy-2,6, 6-trimethylcyclohexen-1-yl]-1-[(1R,4S)-4-hydroxy-1,2, 2-trimethylcyclopentyl]-4,8,13,17-tetramethylnonadeca-2,4,6,8,10,12,14, 16,18-nonaen-1-one

Synonym

(3R,3'S,5'R)-3,3'-dihydroxy-β,κ-caroten-6'one, Paprika extract

Solubility

Insoluble in water. Soluble in oil. Soluble in acetone.

Appearance

Dark Red oil liquid

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C0260 MSDS PDF

Info Sheet

C0260 Info Sheet PDF

References

Zhang X, Zhao WE, Hu L, et al. Carotenoids inhibit proliferation and regulate expression of peroxisome proliferators-activated receptor gamma (PPARγ) in K562 cancer cells. Arch Biochem Biophys. 2011 Aug 1;512(1):96-106. PMID: 21620794.

Aizawa K, Inakuma T. Dietary capsanthin, the main carotenoid in paprika (Capsicum annuum), alters plasma high-density lipoprotein-cholesterol levels and hepatic gene expression in rats. Br J Nutr. 2009 Dec;102(12):1760-6. PMID: 19646292.

Maoka T, Mochida K, Kozuka M, et al. Cancer chemopreventive activity of carotenoids in the fruits of red paprika Capsicum annuum L. Cancer Lett. 2001 Oct 30;172(2):103-9. PMID: 11566483.

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