Description
Abacavir is a guanosine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. Abacavir exhibits antiviral activity. This compound also inhibits guanylyl cyclase and telomerase activity.
Product Unit Size | Cost | Quantity | Stock |
---|
Abacavir is a guanosine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. Abacavir exhibits antiviral activity. This compound also inhibits guanylyl cyclase and telomerase activity.
Cas No. | 188062-50-2 |
---|---|
Purity | ≥98% |
Formula | (C14H18N6O)2 • H2O4S |
Formula Wt. | 670.75 |
IUPAC Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol;sulfuric acid |
Synonym | Abacavir hemisulfate |
Solubility | 0.15mg/mL in DMSO |
Appearance | White to off white powder |
Store Temp | Ambient |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet | |
Brochures |
Leeansyah E, Cameron PU, Solomon A, et al. Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis. 2013 Apr;207(7):1157-65. PMID: 23303810.
Baum PD, Sullam PM, Stoddart CA, et al. Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase. AIDS. 2011 Nov 28;25(18):2243-8. PMID: 21941165.
Ribera E, Tuset M, Martín M, et al. Characteristics of antiretroviral drugs. Enferm Infecc Microbiol Clin. 2011 May;29(5):362-91. PMID: 21531048.
Endogenous coenzyme, unit of cellular energy, r...
Alkaloid produced by Streptomyces, precursor in...
RyR agonist, SIRT, telomerase, P2Y, GPCR inhibi...
Non-nucleoside RT inhibitor.
B-Raf and c-Raf inhibitor.
Methoxy aminopropyl carbazole, neuroprotective....
TRPV4 agonist
BRD2/3/4 inhibitor.
GSK3 and AChE inhibitor, potential σ1 agonist....
Rapamycin analog
PI3K and PDK1 inhibitor.
Recombinant HIV core protein antigen fragment.<...
Fumaric acid methyl ester; nAChR agonist, indir...
MDM2 inhibitor.
Triazole; 14-α demethylase inhibitor, potentia...
O-methylated coumarin; Ca2+ channel blocker.
MEK1/2 inhibitor.
Impurity of everolimus
Recombinant HIV glycoprotein antigen fragment.<...
Deubiquitinating enzyme inhibitor.