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Aceclofenac

Aceclofenac

Product ID A1017
Cas No. 89796-99-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $71.50 In stock
5 g $111.20 In stock
25 g $433.90 In stock
100 g $929.80 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Aceclofenac is a diclofenac analog that exhibits anti-inflammatory and analgesic activities. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that somewhat selectively inhibits COX-2; it is clinically used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Aceclofenac downregulates expression of L-selectin, ICAM-3, and CD43, decreasing neutrophil adhesion to endothelial cells.

Product Info

Cas No.

89796-99-6

Purity

≥98%

Formula

C16H13Cl2NO4

Formula Wt.

354.18

Chemical Name

2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester

IUPAC Name

2-[2-[2-(2,6-dichloroanilino)phenyl]acetyl]oxyacetic acid

Synonym

Airtal, Falcol, Gerbin, Preservex

Melting Point

149-150°C

Solubility

Soluble in ethanol and acetone, insoluble in water

Appearance

A White or Almost White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A1017 MSDS PDF

Info Sheet

A1017 Info Sheet PDF

References

Chopade AR, Sayyad FJ, Naikwade NS. Pharmacological characterization of carrageenan induced heat muscle hyperalgesia in rats using non-selective, preferential and selective COX-2 inhibitors. Pharmacol Rep. 2014 Jun;66(3):353-62. PMID: 24905509.

González-Alvaro I, Carmona L, Díaz-González F, et al. Aceclofenac, a new nonsteroidal antiinflammatory drug, decreases the expression and function of some adhesion molecules on human neutrophils. J Rheumatol. 1996 Apr;23(4):723-9. PMID: 8730134.

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