[Ala19]-Glucagon-like Peptide II, rat

Name: [Ala19]-Glucagon-like Peptide II, rat
SKU: G4485
Availability: BackOrder

Product ID G4485

Cas No. 89750-15-2

Purity ≥95%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Glucagon-like peptide 2 (GLP-2) is a peptide hormone primarily synthesized in the intestine and pancreas. GLP-2 binds and activates the GLP-2 receptor, exhibiting vasodilatory, antihypertensive, antidepressant, and gastrointestinal motility modulating activities. In animal models, GLP-2 increases intestinal blood flow and decreases mean arterial blood pressure. GLP-2 potentiates L-type voltage-gated Ca2+ channels through a mechanism that involves activation of PKA. Additionally, GLP-2 decreases immobility time in animals undergoing the forced swim test. This peptide stimulates cell proliferation, inhibiting chemotherapy-induced mucosal atrophy in the intestines. GLP-2 also decreases gastric emptying and gastrointestinal motility.

Product Info

Cas No.	89750-15-2
Purity	≥95%
Formula	C₁₆₅H₂₅₄N₄₄O₅₅S
Formula Wt.	3766.2
Synonym	GLP-2

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	G4485 MSDS PDF
Info Sheet	G4485 Info Sheet PDF

References

Sasaki-Hamada S, Ito K, Oka JI. Neuronal Fos-like immunoreactivity associated with dexamethasone-induced hypertension in rats and effects of glucagon-like peptide-2. Life Sci. 2013 Oct 24. pii: S0024-3205(13)00618-8. [Epub ahead of print]. PMID: 24513200.

Hansen LB. GLP-2 and mesenteric blood flow. Dan Med J. 2013 May;60(5):B4634. PMID: 23673268.

Rasmussen AR, Viby NE, Hare KJ, et al. The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin. Dig Dis Sci. 2010 Oct;55(10):2785-96. PMID: 20112065.

Wang Y, Guan X. GLP-2 potentiates L-type Ca2+ channel activity associated with stimulated glucose uptake in hippocampal neurons. Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E156-66. PMID: 19920220.

Iwai T, Hayashi Y, Narita S, et al. Antidepressant-like effects of glucagon-like peptide-2 in mice occur via monoamine pathways. Behav Brain Res. 2009 Dec 1;204(1):235-40. PMID: 19539656.

Mojsov S, Kopczynski MG, Habener JF. Both amidated and nonamidated forms of glucagon-like peptide I are synthesized in the rat intestine and the pancreas. J Biol Chem. 1990 May 15;265(14):8001-8. PMID: 1692320.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Comments
This field is for validation purposes and should be left unchanged.

[Ala19]-Glucagon-like Peptide II, rat

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Ampicillin Trihydrate

Cuelure

4-Aminosalicylic Sodium Dihydrate

VX-765

L-Cystine

I-BET-762

Pazopanib

TGR5 Receptor Agonist

Tibolone

WIN 55,212-2 Mesylate

Isoimperatorin

Myricetin

Venlafaxine Hydrochloride

Satraplatin

SB-203580

Neuropeptide FF

Enramycin B

Piperacillin Sodium

Tenovin-6

Stresscopin-Related Peptide, human

Footer