Description
Alloxan is an oxygenated pyrimidine and toxic analog of glucose. Alloxan destroys β cells and is used in research models to induce diabetes. This compound does not affect human cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Alloxan is an oxygenated pyrimidine and toxic analog of glucose. Alloxan destroys β cells and is used in research models to induce diabetes. This compound does not affect human cells.
| Cas No. | 2244-11-3 |
|---|---|
| Purity | ≥98% |
| Formula | C4H2N2O4 • H2O |
| Formula Wt. | 160.08 |
| Chemical Name | 2,4,5,6(1H,3H)-pyrimidinetetrone monohydrate |
| IUPAC Name | 5,5-dihydroxy-1,3-diazinane-2,4,6-trione |
| Synonym | Alloxan |
| Melting Point | 255°C |
| Solubility | Soluble in water. |
| Appearance | Tan Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Franzén S, Friederich-Persson M, Fasching A, et al. Differences in susceptibility to develop parameters of diabetic nephropathy in four mouse strains with type 1 diabetes. Am J Physiol Renal Physiol. 2014 May 15;306(10):F1171-8. PMID: 24623147.
Tyrberg B, Andersson A, Borg LA. Species differences in susceptibility of transplanted and cultured pancreatic islets to the beta-cell toxin alloxan. Gen Comp Endocrinol. 2001 Jun;122(3):238-51. PMID: 11356036.
Eizirik DL, Pipeleers DG, Ling Z, et al. Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9253-6. PMID: 7937750.
HDAC6/10 inhibitor.
Smo inhibitor.
Electron carrier used to study dehydrogenase el...
Endogenous purine nucleotide base, required for...
Organosulfur found in garlic; Microtubule polym...
Smo inhibitor.
Viral M2 proton channel blocker, MAO-A, NET, NM...
Avermectin; glu-gated Cl- channel activator, Gl...
V600E B-Raf inhibitor.
c-MET inhibitor.
ROCK inhibitor.
Iron chelator.
Cephalosporin analogue
Endogenous peptide hormone fragment, involved i...
5-HT1B/1D agonist.
Cyclic peptide mycotoxin produced by Alternaria...
Neuropeptide hormone found in arthropods.
Nitrofuran derivative.
Found in Taxus, starting material for synthesis...
Modified nucleotide used for labeling DNA; DNA ...