• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Amlodipine

Amlodipine

Product ID A5045
Cas No. 88150-42-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $102.00 In stock
5 g $367.30 In stock
10 g $459.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amlodipine is a dihydropyridine L-type Ca2+ channel blocker that exhibits antihypertensive, anti-anginal, and vasodilatory activities. Amlodipine is clinically used to treat hypertension and angina as it induces relaxation of arterial smooth muscles, decreases blood pressure, and increases blood flow to the heart. Amlodipine also inhibits acid sphingomyelinase (FIASMA), which is involved in programmed cell death. Additionally, this compound improves smooth muscle hypertrophy and collagen deposition, preventing arterial remodeling in hypertensive rats.

Product Info

Cas No.

88150-42-9

Purity

≥98%

Formula

C20H25ClN2O5

Formula Wt.

408.88

Chemical Name

2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

IUPAC Name

3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1, 4-dihydropyridine-3,5-dicarboxylate

Synonym

UK-48340

Melting Point

134-136°C

Solubility

Soluble in methanol, ethanol (82mg/mL)choroform and DMSO (82mg/mL).

Appearance

Almost White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5045 MSDS PDF

Info Sheet

A5045 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

Fan YY, Kohno M, Nakano D, et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens. 2010 May;28(5):1034-1043. PMID: 20411599.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O9497

    Oxytocin

    Endogenous neuropeptide hormone, involved in so...

    ≥95%
  • V0148

    Valproic Acid

    T-type Ca2+ and voltage-gated Na+ channel block...

    ≥98%
  • B8676

    BVT-2733

    11β-HSD1 inhibitor.

    ≥98%
  • D4873

    Meso-2,3-dimercaptosuccinic Acid

    Organosulfur, chelating agent.

    ≥98%
  • G1200

    GDC-0068

    Akt inhibitor.

    ≥98%
  • A0918

    N-Acetyl-L-Cysteine

    Cysteine derivative, antioxidant, ROS scavenger...

    ≥98%
  • O4578

    Oltipraz

    Antioxidant; Nrf2 activator.

    ≥98%
  • A5302

    Anastrozole

    Aromatase inhibitor.

    ≥99%
  • D5649

    Domperidone

    D2/3 antagonist, hERG K+ channel blocker.

    ≥98%
  • C2540

    CGK 733

    ATM and ATR inhibitor.

    ≥98%
  • P3469

    Pirfenidone

    Collagen synthesis inhibitor.

    ≥98%
  • T6834

    Triacsin C

    Acyl-CoA synthetase inhibitor.

    ≥95%
  • H9863

    Hyperforin Dicyclohexylammonium

    Stable salt form of hyperforin, a compound foun...

    ≥97%
  • C0369

    Cardiogenol C Hydrochloride

    Induces cardiomyogenic effects in pluripotent c...

    ≥98%
  • C0800

    C59

    PORCN inhibitor.

    ≥98%
  • T1673

    Terlipressin Acetate

    Synthetic peptide, vasopressin analog; AVPR1 ag...

    ≥95%
  • C104762

    CCT-245737

    CHK1 inhibitor.

    ≥98%
  • Z1970

    Zerumbone

    Cyclic sesquiterpene found in ginger root; pote...

    ≥99%
  • C9711

    Cyclovirobuxine D

    Found in Buxus; hERG K+ channel inhibitor.

    ≥97%
  • P8118

    Puerarin

    Isoflavone daidzein derivative found in Puerari...

    ≥96%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only