• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Anacetrapib

Anacetrapib

Product ID A5301
Cas No. 875446-37-0
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $157.50 In stock
10 mg $257.30 In stock
25 mg $472.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Anacetrapib is a cholesterol ester transfer protein (CETP) inhibitor that exhibits anti-atherosclerotic activity. In vivo, anacetrapib inhibits the development of atherosclerosis and decreases levels of VLDL and PCSK9. In a clinical setting, this compound decreases levels of LDL and ApoB. Additionally, anacetrapib may increase levels of HDL and ApoA1.

Product Info

Cas No.

875446-37-0

Purity

≥98%

Formula

C30H25F10NO3

Formula Wt.

637.52

Chemical Name

(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one

IUPAC Name

(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one

Synonym

MK-0859

Solubility

DMSO 200mM Ethanol 200mM Water Insoluble

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A5301 MSDS PDF

Info Sheet

A5301 Info Sheet PDF

References

van der Tuin SJ, Kühnast S, Berbée JF, et al. Anacetrapib reduces (V)LDL cholesterol by inhibition of CETP activity and reduction of plasma PCSK9. J Lipid Res. 2015 Nov;56(11):2085-93. PMID: 26342106.

Millar JS, Reyes-Soffer G, Jumes P, et al. Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. J Clin Invest. 2015 Jun;125(6):2510-22. PMID: 25961461.

Äijänen T, Koivuniemi A, Javanainen M, et al. How anacetrapib inhibits the activity of the cholesteryl ester transfer protein? Perspective through atomistic simulations. PLoS Comput Biol. 2014 Nov 20;10(11):e1003987. PMID: 25412509.

Hooper AJ, Burnett JR. Anacetrapib, a cholesteryl ester transfer protein inhibitor. Expert Opin Investig Drugs. 2012 Jan;21(1):103-9. PMID: 22191425.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • J0274

    Jasplakinolide

    Marine toxin; actin polymerization inducer.

    ≥98%
  • N1721

    Nefiracetam

    Pyrrolidone; NMDA and mGluR5 agonist, N-type an...

    ≥98%
  • P9671

    Pyrazinamide

    Nicotinamide analog prodrug; fatty acid synthet...

    ≥98%
  • N3208

    Nicardipine

    Dihydropyridine; L-type Ca2+ channel blocker.

    ≥99%
  • G062680

    GBR-12909 Dihydrochloride

    Dopamine reuptake inhibitor (DRI).

    ≥98%
  • T5869

    Torcetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • T3468

    Tirapazamine

    Topoisomerase II inhibitor, RPA modulator.

    ≥98%
  • S6129

    D-Sphingosine

    Endogenous component of sphingolipids; PKC inhi...

    ≥98%
  • S8248

    Sulfamethoxazole

    Sulfonamide; PABA inhibitor.

    ≥98%
  • T0101

    7-epi-10-Deacetyltaxol

    Taxane found in Taxus; potential microtubule de...

    ≥98%
  • P2410

    Phenethyl Dimethyl Caffeate

    Caffeic acid derivative.

    ≥98%
  • S760004

    Stachybotrylactam

    Spirodihydrobenzofuranlactam

    ≥98%
  • M177531

    Menaquinone-9

    2-methyl-1,4-naphthoquinone derivative

    ≥99%
  • A5133

    Amiloride Hydrochloride Dihydrate

    K+-sparing diuretic; ENaC and acid-sensing ion ...

    ≥98%
  • V024761

    Vatalanib

    Inhibitor of VEGFR1/2/3.

    ≥98%
  • T0253

    Tangeretin

    Polymethoxy flavonoid found in citrus fruits.

    ≥98%
  • T1679

    Tetracycline Hydrochloride

    Polyketide; protein translation inhibitor, mamm...

    ≥95%
  • D0375

    Dasatinib Monohydrate

    Abl, PDGFR, EphR, Src, k-Kit, FYN, LCK, HCK inh...

    ≥98%
  • O4402

    Olaparib

    PARP1/2 inhibitor.

    ≥98%
  • M9608

    Myclobutanil

    14-α demethylase inhibitor.

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only