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Aprotinin

Product ID A6268
Cas No. 9087-70-1
Purity ≥ 5400 u/mg
Product Unit SizeCostQuantityStock
10 mg $141.80 In stock
50 mg $604.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Aprotinin is a polypeptide that exhibits anti-fibrinolytic (pro-coagulant) activity. Aprotinin inhibits serine proteases such as trypsin, chymotrypsin, plasmin, and kallikrein. Inhibiting these proteases prevents formation of Factor XIIa and prevents breakdown of blood clots. Aprotinin is clinically used during surgeries to prevent bleeding.

Product Info

Cas No.

9087-70-1

Purity

≥ 5400 u/mg

Formula

C284H432N84O79S7

Formula Wt.

6511.44

Synonym

Pancreatic trypsin inhibitor, Antagosan, Fosten, Iniprol, Repulson, Trazinin, Zymofren

Solubility

Soluble in water (10 mg/ml).

Appearance

White to light yellow powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A6268 MSDS PDF

Info Sheet

A6268 Info Sheet PDF

References

Shiga T, Wajima Z, Inoue T, et al. Aprotinin in major orthopedic surgery: a systematic review of randomized controlled trials. Anesth Analg. 2005 Dec;101(6):1602-7. PMID: 16301226.

Mahdy AM, Webster NR. Perioperative systemic haemostatic agents. Br J Anaesth. 2004 Dec;93(6):842-58. PMID: 15277296.

Kassell B, Laskowski M Sr. The basic trypsin inhibitor of bovine pancreas. V. The disulfide linkages. Biochem Biophys Res Commun. 1965 Aug 16;20(4):463-8. PMID: 5860161.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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