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Oxaliplatin

Oxaliplatin

Product ID O9201
Cas No. 61825-94-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $52.50 In stock
25 mg $112.60 In stock
100 mg $217.90 In stock
500 mg $563.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
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  • Custom Order

Description

Oxaliplatin is a platinum-based cross-linking agent that exhibits anticancer chemotherapeutic activity. Oxaliplatin inhibits DNA replication and transcription and is clinically used to treat colon cancer. In hepatocellular carcinoma cells, oxaliplatin induces S phase cell cycle arrest, downregulates expression of CDK4 and cyclin D1, upregulates expression of p21 and p53, and inhibits cellular proliferation.

Product Info

Cas No.

61825-94-3

Purity

≥98%

Formula

C8H14N2O4Pt

Formula Wt.

397.29

Chemical Name

(SP-4-2)-[(1R,2R)-1.2-Cyclohexanediamine-κN,κN']- [ethanedioato(2-)-κO1,κO2]platinum

Synonym

Oxalatoplatin, Oxalatoplatinum

Melting Point

260°C

Solubility

Soluble in water (10 mM, 4 mg/mL), DMSO (50 mM or 20 mg /mL).

Appearance

White Crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

O9201 MSDS PDF

Info Sheet

O9201 Info Sheet PDF

References

Chen X, Wu Y, Dong H, et al. Platinum-based agents for individualized cancer treatment. Curr Mol Med. 2013 Dec;13(10):1603-12. PMID: 24206132.

Gao J, Wang R, Yang Q, et al. Effect of Oxaliplatin on cell cycle of hepatocellular carcinoma cell line HepG2. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013 Jul;42(4):437-42. PMID: 24022933.

Graham J, Mushin M, Kirkpatrick P. Oxaliplatin. Nat Rev Drug Discov. 2004 Jan;3(1):11-2. PMID: 14756144.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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