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Atglistatin

Product ID A7725
Cas No. 1469924-27-3
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $114.80 Please Inquire
25 mg $444.10 Please Inquire
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Atglistatin is an inhibitor of adipose triglyceride lipase (ATGL) that decreases fatty acid mobilization and prevents lipolysis. Atglistatin also prevents triglyceride accumulation after acute myocardial infarction, displaying cardioprotective benefit.

Product Info

Cas No.

1469924-27-3

Purity

≥98%

Formula

C17H21N3O

Formula Wt.

283.38

IUPAC Name

3-[4'-(Dimethylamino)-3-biphenylyl]-1,1-dimethylurea

Solubility

The solubility of atglistatin in ethanol is approximately 3 mg/ml and approximately 5 mg/ml in DMSO and DMF.

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

A7725 MSDS PDF

Info Sheet

A7725 Info Sheet PDF

References

Zhang H, Sun T, Jiang X, et al. PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL. J Transl Med. 2015 Feb 21;13:68. PMID: 25890298.

Cerk IK, Salzburger B, Boeszoermenyi A, et al. A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase. J Biol Chem. 2014 Nov 21;289(47):32559-70. PMID: 25258314.

Mayer N, Schweiger M, Romauch M, et al. Development of small-molecule inhibitors targeting adipose triglyceride lipase. Nat Chem Biol. 2013 Dec;9(12):785-7. PMID: 24096302.

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