Description
Atosiban is an antagonist at oxytocin and vasopressin receptors, exhibiting tocolytic activity. Atosiban is clinically used to decrease uterine contractility in the prevention of preterm birth.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Atosiban is an antagonist at oxytocin and vasopressin receptors, exhibiting tocolytic activity. Atosiban is clinically used to decrease uterine contractility in the prevention of preterm birth.
| Cas No. | 914453-95-5 |
|---|---|
| Purity | ≥95% |
| Formula | C43H67N11O12S2 |
| Formula Wt. | 994.2 |
| IUPAC Name | acetic acid;(2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2- yl]-1-[(4R,7S,13S, 16R)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-ethoxyphenyl) methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8, 11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide |
| Solubility | Soluble in water, DMSO, methanol. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Usta IM, Khalil A, Nassar AH. Oxytocin antagonists for the management of preterm birth: a review. Am J Perinatol. 2011 Jun;28(6):449-60. PMID: 21170825.
Pierzynski P. Oxytocin and vasopressin V(1A) receptors as new therapeutic targets in assisted reproduction. Reprod Biomed Online. 2011 Jan;22(1):9-16. PMID: 21130036.
Endogenous steroid hormone, involved in regulat...
DAT inhibitor.
PKD inhibitor.
Peptide, involved in synapse formation and cell...
Endogenous peptide hormone; guanyl cyclase C ag...
Synthetic cafestol derivative.
Synthesis impurity
Chalcone kavalactone found in Piper methysticum...
Coumarin; VKORC1 inhibitor.
Quinazoline; α1-adrenergic antagonist.
5-HT1A and σ1/2 agonist, 5-HT2A/2C/6/7, D1-4, ...
Immunomodulator; teratogen.
Casein kinase 2 inhibitor.
Toxin produced by Canarthis vesicatoria; PP1/2A...
Downregulates LPS-stimulated expression of pro-...
Ansamycin; bacterial DNA-dependent RNA polymera...
H+/K+ ATPase and ROCK-2 inhibitor.
Building block
Cembranoid diterpene found in Sarcophyton glauc...
ITC, erysolin analog.