• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Azelaic Acid

Azelaic Acid

Product ID A9817
Cas No. 123-99-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $41.00 In stock
25 g $71.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Azelaic acid is a dicarboxylic acid originally found in Arabidopsis that exhibits anti-inflammatory activity. Azelaic acid is clinically used to treat rosacea, acne, and hyperpigmentary disorders. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARγ is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays anticancer potential as well, inhibiting the proliferation of cutaneous melanoma cells due to suppression of mitochondrial oxidoreductive activity and DNA synthesis.

Product Info

Cas No.

123-99-9

Purity

≥98%

Formula

C9H16O4

Formula Wt.

188.22

Chemical Name

Nonanedioic acid

IUPAC Name

nonanedioic acid

Synonym

1,7-heptanedicarboxylic acid, Anchoic acid, Azelex

Melting Point

106.5°C

Solubility

Soluble in boiling water and alcohol

Appearance

A White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A9817 MSDS PDF

Info Sheet

A9817 Info Sheet PDF

References

Coda AB, Hata T, Miller J, et al. Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. J Am Acad Dermatol. 2013 Oct;69(4):570-7. PMID: 23871720.

Briganti S, Flori E, Mastrofrancesco A, et al. Azelaic acid reduced senescence-like phenotype in photo-irradiated human dermal fibroblasts: possible implication of PPARγ. Exp Dermatol. 2013 Jan;22(1):41-7. PMID: 23278893.

Fitton A, Goa KL. Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. Drugs. 1991 May;41(5):780-98. PMID: 1712709.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F1745

    Felodipine

    Dihydropyridine; L-type Ca2+ channel blocker.

    ≥98%
  • A1370

    Adrenomedullin (22-52), human

    Endogenous peptide hormone, involved in cell gr...

    ≥95%
  • P2997

    Phytic Acid, 40-50 wt% aqueous solution

    Saturated cyclic acid used to store phosphorus ...

    ≥40%
  • A4544

    Allyl Disulfide

    Organosulfur found in garlic.

    ≥98%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.

    ≥98%
  • O486179

    Omeprazole Impurity C

    Impurity of omeprazole

    ≥99%
  • A5287

    Angiotensinogen (1-14), human

    Peptide fragment, renin substrate, precursor to...

    ≥95%
  • C9778

    Cytarabine

    Pyrimidine nucleoside (cytidine) analog; DNA ch...

    ≥98%
  • N344784

    N-Nitroso Valsartan

    Valsartan impurity

    ≥98%
  • G0246

    Galantamine Hydrobromide

    Alkaloid found in Galanthus, Narcissus, Leucoju...

    ≥98%
  • O9702

    Ozagrel Hydrochloride

    TxA2 synthase inhibitor.

    ≥98%
  • C0365

    Carvedilol

    FIASMA; α1- and β1/2-adrenergic antagonist.

    ≥98%
  • A040068

    AB-680

    CD73 inhibitor

    ≥98%
  • G7442

    GSK-343

    EZH2 HMT inhibitor.

    ≥98%
  • S2792

    SGX-523

    MET inhibitor.

    ≥98%
  • M5877

    Motesanib Diphosphate

    VEGFR, PDGFR, c-Kit, RET inhibitor.

    ≥98%
  • Z3444

    Zileuton

    5-Lipoxygenase inhibitor.

    ≥98%
  • M5727

    Moguisteine

    Potential ATP-sensitive K+ channel blocker, pot...

    ≥98%
  • T6817

    D(+)-Trehalose Dihydrate

    α-Linked disaccharide composed of α-glucose u...

    ≥98%
  • E537335

    Enniatin B1

    Mycotoxin contaminant found in cereal grains.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only