Description
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Product Unit Size | Cost | Quantity | Stock |
|---|
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Cas No. | 173101-56-9 |
|---|---|
| Purity | ≥95% |
| Formula | C48H53NO14 |
| Formula Wt. | 867.93 |
| IUPAC Name | [4,12-diacetyloxy-1,9-dihydroxy-15-[2-hydroxy-3-phenyl-3-[(2-phenylacetyl)amino]propanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Synonym | Taxol F; Paclitaxel impurity P; |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.
Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.
Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.
Endogenous purine derivative of xanthine.
Endogenous peptide hormone, involved in stress ...
Peptide hormone, neurotensin analog found in am...
SV2A synaptic vesicle inhibitor.
Selective inhibitor of the delta isoform of PI3...
Inhibitor of VEGFR and FGFR.
Nucleoside antibiotic mixture; GlcNAc phosphotr...
p110α PI3K and mTOR inhibitor.
DAT inhibitor.
Iron chelator.
ATM and ATR inhibitor.
Diterpene found in Taxus.
Bisphosphonate; squalene synthase inhibitor.
Camptothecin derivative; topoisomerase I inhibi...
Calcium channel blocker.
Peptide, carbonic anhydrase G250 epitope.
Synthetic steroid; glucocorticoid agonist.
MEK1/2 inhibitor.
Ca2+-sensing receptor agonist.
CHK1 inhibitor.