Description
This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Product Unit Size | Cost | Quantity | Stock |
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This compound is a benzyl analog of taxol. Like other taxanes, this compound may also promote microtubule polymerization and prevent microtubule depolymerization, exhibiting anticancer activity.
| Cas No. | 173101-56-9 |
|---|---|
| Purity | ≥95% |
| Formula | C48H53NO14 |
| Formula Wt. | 867.93 |
| IUPAC Name | [4,12-diacetyloxy-1,9-dihydroxy-15-[2-hydroxy-3-phenyl-3-[(2-phenylacetyl)amino]propanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Synonym | Taxol F; Paclitaxel impurity P; |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Li Y, Qin F, Wang SM, et al. Chemical studies on Taxus canadensis. Chem Biodivers. 2013 Oct;10(10):1729-53. PMID: 24130020.
Orr GA, Verdier-Pinard P, McDaid H, et al. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003 Oct 20;22(47):7280-95. PMID: 14576838.
Jordan MA. Mechanism of action of antitumor drugs that interact with microtubules and tubulin. Curr Med Chem Anticancer Agents. 2002 Jan;2(1):1-17. PMID: 12678749.
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