• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Bleomycin A5 Hydrochloride

Bleomycin A5 Hydrochloride

Product ID B4517
Cas No. 55658-47-4
Purity ≥90%
Product Unit SizeCostQuantityStock
1 mg $121.30 In stock
5 mg $373.80 In stock
10 mg $654.90 In stock
25 mg $1,100.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Bleomycin A5 is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin is clinically used to treat lymphomas, squamous cell carcinomas, and testicular cancer. Additionally, this compound induces apoptosis, alters cell cycle regulation, inhibits proliferation, and decreases tumor size in cellular and animal models of hemangioma. Bleomycin may also inhibit thioredoxin reductase.

Product Info

Cas No.

55658-47-4

Purity

≥90%

Formula

C57H89N19O21S2 • HCl

Formula Wt.

1477.02

Chemical Name

Bleomycin A5 Hydrochloride

IUPAC Name

[2-[2-[2-[[6-amino-2-[3-amino-1-[(2, 3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl] amino]-3-[[5-[[1-[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1, 3-thiazol-2-yl]-1, 3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4- methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4, 5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3, 5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate;hydrochloride InChI: InChI=1S/C57H89N19O21S2.ClH/c1-22-35(73-48(76-46(22)61)27(14-33(60)80) 68-15-26(59)47(62)86)52(90)75-37(43(28-16-65-21-69-28)95-56-45(41(84)39 (82)31(17-77)94-56)96-55-42(85)44(97-57(63)92)40(83)32(18-78)93-55)53 (91)70-24(3)38(81)23(2)49(87)74-36(25(4)79)51(89)67-13-8-34-71-30(20-98- 34)54-72-29(19-99-54)50(88)66-12-7-11-64-10-6-5-9-58;/h16,19-21,23-27, 31-32,36-45,55-56,64,68,77-79,81-85H,5-15,17-18,58-59H2,1-4H3,(H2,60, 80)(H2,62,86)(H2,63,92)(H,65,69)(H,66,88)(H,67,89)(H,70,91)(H,74,87)(H, 75,90)(H2,61,73,76);1H

Synonym

Pingyangmycin hydrochloride

Solubility

Freely soluble in water, slightly soluble in ethanol

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

B4517 MSDS PDF

Info Sheet

B4517 Info Sheet PDF

References

Li P, Li DF, Guo ZT, et al. Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study. Zhonghua Kou Qiang Yi Xue Za Zhi. 2013 Jan;48(1):18-22. PMID: 23534516.

Yang Y, Sun M, Ma Q, et al. Bleomycin A5 sclerotherapy for cervicofacial lymphatic malformations. J Vasc Surg. 2011 Jan;53(1):150-5. PMID: 20843632.

Liu Y, Wu F, Zou G. Electrophoresis mobility shift assay and biosensor used in studying the interaction between bleomycin A5 and DNA. Anal Chim Acta. 2007 Sep 19;599(2):310-4. PMID: 17870295.

Vorobjev PE, Smith JB, Pyshnaya IA, et al. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec;14(6):1307-13. PMID: 14624648.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • N1757

    Neostigmine Bromide

    AChE inhibitor.

    ≥92%
  • D3420

    4-(3,4-Difluorobenzo)curcumin

    Curcumin derivative.

    ≥95%
  • A4400

    Alamethicin

    Antimicrobial peptide found in Trichoderma, ind...

    ≥95%
  • A4675

    Alternariol

    Mycotoxin produced by Alternaria; topoisomerase...

    ≥98%
  • I5212

    Indirubin

    Bisindole isomer of indigo found in Indigo natu...

    ≥98%
  • G4662

    GLPG-0634

    JAK1 inhibitor.

    ≥98%
  • G016499

    2’,3’-cGAMP Sodium Salt

    Agonist of STING.

    ≥99%
  • E544766

    Enterocin

    A bacteriocin

    ≥95%
  • S8245

    Sulfadiazine

    Sulfonamide; folate production inhibitor.

    ≥98%
  • C0270

    Carbamazepine

    GABA potentiator, voltage-gated Na+ and ATP-sen...

    ≥98%
  • L5660

    Loperamide Hydrochloride

    FIASMA, μOR agonist, potential HCN channel blo...

    ≥98%
  • O9396

    Oxytetracycline

    Tetracycline; protein translation inhibitor.

    ≥96%
  • R3477

    Ritodrine Hydrochloride

    Phenylethylamine; β2-adrenergic agonist, SK/BK...

    ≥98%
  • A4806

    Ambroxol Hydrochloride

    Expectorant.

    ≥98%
  • C9773

    L-Cystine

    Endogenous amino acid, forms disulfide bridges ...

    ≥98%
  • M7530

    [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone

    Semi-synthetic peptide, melanocortin analog; MC...

    ≥98%
  • L1881

    Leuprolide Acetate

    GnRH analog; GnRH1 agonist.

    ≥95%
  • R2714

    Recombinant HCV-NS5 Antigens

    Recombinant HCV antigen fragment.

    ≥95%
  • C0016

    Caerulomycin A

    Bipyridamine toxin.

    ≥96%
  • T9969

    Tyrphostin AG490

    JAK2 inhibitor, potential EGFR inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only