Description
Bohemine is a purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Bohemine suppresses cell growth and induces G1 and G2 phase cell cycle arrest in hybridoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Bohemine is a purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Bohemine suppresses cell growth and induces G1 and G2 phase cell cycle arrest in hybridoma cells.
| Cas No. | 189232-42-6 |
|---|---|
| Purity | ≥98% |
| Formula | C18H24N6O |
| Formula Wt. | 340.43 |
| Chemical Name | 3-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)propan-1-ol |
| IUPAC Name | 3-{[6-(Benzylamino)-9-isopropyl-9H-purin-2-yl]amino}-1-propanol |
| Synonym | 3-{[6-(benzylamino)-9-(propan-2-yl)-9h-purin-2-yl]amino}propan-1-ol; CHEMBL83980; CHEBI:86007 |
| Solubility | >17mg/ml in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kovarova H, Halada P, Man P, et al. Application of proteomics in the search for novel proteins associated with the anti-cancer effect of the synthetic cyclin-dependent kinases inhibitor, bohemine. Technol Cancer Res Treat. 2002 Aug;1(4):247-56. PMID: 12625783.
Franek F, Strnad M, Havlícek L, et al. Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture. Cytotechnology. 2001 Jul;36(1-3):117-23. PMID: 19003322.
Benzimidazole; microtubule polymerization inhib...
NSAID; COX-2 inhibitor.
Hydrazine derivative, DNA alkylator; MAO inhibi...
Dipeptide ester, commercial sweetener.
Coumarin; VKORC1 inhibitor.
Dihydropyridine; L-type Ca2+ channel blocker.
Mast cell stabilizer; histamine H1/2/3 antagoni...
Niacin derivative.
Glutathione-S-transferase inhibitor.
Peptide, derivative of AT II, involved in vasoc...
Endogenous peptide hormone, increases extracell...
Saponin found in Bupleurum, Heteromorpha, and S...
Peptide, protease substrate.
Endogenous peptide, cleavage product of AT II; ...
Peptide produced in tomato leaves; potential ca...
RAD51 inhibitor.
β-lactam; penicillin binding protein inhibitor...
β-lactam cephalosporin; penicillin binding pro...
Endogenous peptide hormone, GLP-1 fragment, inv...
AurKA/B inhibitor.