Description
Bohemine is a purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Bohemine suppresses cell growth and induces G1 and G2 phase cell cycle arrest in hybridoma cells.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Bohemine is a purine derivative that inhibits cyclin-dependent kinases (CDKs) and exhibits anticancer activity. Bohemine suppresses cell growth and induces G1 and G2 phase cell cycle arrest in hybridoma cells.
| Cas No. | 189232-42-6 |
|---|---|
| Purity | ≥98% |
| Formula | C18H24N6O |
| Formula Wt. | 340.43 |
| Chemical Name | 3-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)propan-1-ol |
| IUPAC Name | 3-{[6-(Benzylamino)-9-isopropyl-9H-purin-2-yl]amino}-1-propanol |
| Synonym | 3-{[6-(benzylamino)-9-(propan-2-yl)-9h-purin-2-yl]amino}propan-1-ol; CHEMBL83980; CHEBI:86007 |
| Solubility | >17mg/ml in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Kovarova H, Halada P, Man P, et al. Application of proteomics in the search for novel proteins associated with the anti-cancer effect of the synthetic cyclin-dependent kinases inhibitor, bohemine. Technol Cancer Res Treat. 2002 Aug;1(4):247-56. PMID: 12625783.
Franek F, Strnad M, Havlícek L, et al. Diverse effects of the cyclin-dependent kinase inhibitor bohemine: Concentration- and time-dependent suppression or stimulation of hybridoma culture. Cytotechnology. 2001 Jul;36(1-3):117-23. PMID: 19003322.
PP2A activator, Sphk1 and PKC inhibitor.
BH3 mimetic; Bcl-2 and Bcl-xl inhibitor.
VEGF-C/Nrp2 inhibitor. Leukotriene receptor ant...
Macrolide; peptidyl transferase inhibitor, prot...
Cyclic depsipeptide is a secondary metabolite i...
MEK inhibitor.
Steroid; glucocorticoid agonist.
Fluoroquinolone; bacterial DNA gyrase inhibitor...
NSAID; COX-1/2 inhibitor.
K+ channel blocker, catecholamine release stimu...
JAK2 inhibitor
Alkaloid found in Galanthus, Narcissus, Leucoju...
Alters membrane permeability, prevents transpor...
Peptide, involved in paracrine and autocrine ce...
PI3K and mTOR inhibitor.
Chloramphenicol derivative; protein translation...
MET and GSK-3α/β inhibitor.
Derivative of aloe-emodin, anthraquinone found ...
EGFR inhibitor.
Galactose-derived hexosamine sugar, component o...