Description
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
| Cas No. | 702675-74-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H26IN7O2S |
| Formula Wt. | 591.47 |
| Chemical Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| IUPAC Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| Synonym | BX795 |
| Solubility | DMSO 100 mg/mL (169.07 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Feldman RI, Wu JM, Polokoff MA, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem. 2005 May 20;280(20):19867-74. PMID: 15772071.
Thiamine, coccidiostat; thiamine transporter in...
Terpene lactone found in Ginkgo.
Neurotoxin frequently used to aid in modeling P...
c-Raf, RET, VEGFR1 inhibitor, potential HMT inh...
Indoleamine-2,3-dioxygenase inhibitor.
MDM2 inhibitor.
Endogenous opioid peptide; μOR agonist.
Cembranoid diterpene found in Sarcophyton glauc...
Cytarabine derivative, nucleoside (cytosine) an...
NSAID; COX-1/2 and PDE inhibitor.
Juvenile insect hormone mimic.
Akt inhibitor.
Coumarin lactone found in chicory and other pla...
Endogenous calcitonin-family peptide, involved ...
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
GLP-1/GIP receptor co-agonist
Nucleoside (thymidine) analog.
Fibrate; PPARα agonist.
COVID-19 research
Steroid; glucocorticoid agonist.