Description
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
| Cas No. | 702675-74-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H26IN7O2S |
| Formula Wt. | 591.47 |
| Chemical Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| IUPAC Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| Synonym | BX795 |
| Solubility | DMSO 100 mg/mL (169.07 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Feldman RI, Wu JM, Polokoff MA, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem. 2005 May 20;280(20):19867-74. PMID: 15772071.
Cephalomannine derivative found in Taxus; poten...
JAK1/2 inhibitor.
Neuroactive mycotoxin produced by Penicillum an...
Pyrimidine analog; inhibits thymidylate synthas...
Inhibitor of CDK.
Endogenous neuropeptide hormone, involved in so...
GABA potentiator, voltage-gated Na+ and ATP-sen...
Diphenylmethane, inhibits secretion of cortisol...
Side chain attached to various taxanes.
Endogenous calcitonin-family peptide, involved ...
Non-selective CB receptor agonist.
Aminoquinoline, binds heme, causes cell lysis.<...
Lck, Src, SIK inhibitor.
Nucleoside (guanosine) analog; RT, guanylyl cyc...
Fungal pigment found in red yeast rice
Lincosamide; peptidyl transferase inhibitor, pr...
Amide form of vitamin B3 required for productio...
Derivative of methyl caffeate, hydroxycinnamic ...
PI3K inhibitor.
Triterpene sapogenin found in species of Panax;...