Description
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
| Cas No. | 702675-74-9 |
|---|---|
| Purity | ≥98% |
| Formula | C23H26IN7O2S |
| Formula Wt. | 591.47 |
| Chemical Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| IUPAC Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
| Synonym | BX795 |
| Solubility | DMSO 100 mg/mL (169.07 mM) Water Insoluble Ethanol Insoluble |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Feldman RI, Wu JM, Polokoff MA, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem. 2005 May 20;280(20):19867-74. PMID: 15772071.
Alkaloid found in plants in the Amaryllidaceae ...
Polyphenol found in many plants and foods.
PI3K and mTOR inhibitor.
Endogenous opioid peptide; δOR and μOR agonis...
Alcoholic β-glucoside found in willow bark, sa...
β-lactamase inhibitor.
Coumarin; VKORC1 inhibitor.
1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...
Organosulfur, chelating agent.
B-Raf and c-Raf inhibitor.
Selective inhibitor of PI3Kβ and PI3Kδ.
RET, EGFR, VEGFR2 inhibitor.
Triterpene saponin found in species of Panax. <...
Bactericidal
Indole; Src inhibitor.
Thienylbutyl ITC analog.
β-adrenergic agonist.
Selective Cannabinoid receptor 2(CB2) inverse a...
Taxane synthesis intermediate.
Benzothiazepine; L-type Ca2+ channel blocker, p...