Description
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
BX-795 inhibits PDK1, exhibiting anticancer chemotherapeutic activity. BX-795 inhibits Akt signaling, inducing apoptosis and suppressing tumor growth.
Cas No. | 702675-74-9 |
---|---|
Purity | ≥98% |
Formula | C23H26IN7O2S |
Formula Wt. | 591.47 |
Chemical Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
IUPAC Name | N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide |
Synonym | BX795 |
Solubility | DMSO 100 mg/mL (169.07 mM) Water Insoluble Ethanol Insoluble |
Appearance | White to off white powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Feldman RI, Wu JM, Polokoff MA, et al. Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1. J Biol Chem. 2005 May 20;280(20):19867-74. PMID: 15772071.
Sesquiterpene found in Curcuma.
Steroid sulfatase inhibitor.
Venlafaxine metabolite; SERT and NET inhibitor....
Analog of glutamate
Zika Virus antigen
HDAC inhibitor. May reduce blood pressure in hy...
Reversible DNMT1-selective inhibitor
Atazanavir metabolite; HIV protease inhibitor.<...
Triterpene saponin found in Bupleurum.
VEGF-C/Nrp2 inhibitor. Leukotriene receptor ant...
IGF-1R inhibitor.
Alkaloid found in plants in the Amaryllidaceae ...
PI3K and mTOR inhibitor.
Synthetic ITC.
HSP90 inhibitor.
Potential AhR binding agent.
Smac mimetic; IAP inhibitor.
Nucleoside (adenosine) analog; DNA chain termin...
ITC, sulforaphane analog.
Steroid hormone, contraceptive; PR agonist.