• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Endomorphin-2

Endomorphin-2

Product ID E5211
Cas No. 141801-26-5
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $105.00 In stock
10 mg $210.00 In stock
25 mg $420.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Endomorphin-2 is an endogenous agonist at μ-opioid receptors (μORs) in the spinal cord; it exhibits antinociceptive/analgesic, immunosuppressive, and pro-angiogenic activities. Endomorphin-2 increases pain thresholds in animal models of thermal pain and inhibits the formation of antibodies in other cellular models. In HUVECs, this peptide stimulates proliferation, migration, adhesion, and tube formation.

Product Info

Cas No.

141801-26-5

Purity

≥95%

Formula

C32H37N5O5

Formula Wt.

571.68

IUPAC Name

(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide

Solubility

Soluble in water (0.4 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

E5211 MSDS PDF

Info Sheet

E5211 Info Sheet PDF

References

Liu NJ, Gintzler AR. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013 Nov;14(11):1522-30. PMID: 24084000.

Dai X, Song HJ, Cui SG, et al. The stimulative effects of endogenous opioids on endothelial cell proliferation, migration and angiogenesis in vitro. Eur J Pharmacol. 2010 Feb 25;628(1-3):42-50. PMID: 19932695.

Anton B, Leff P, Calva JC, et al. Endomorphin 1 and endomorphin 2 suppress in vitro antibody formation at ultra-low concentrations: anti-peptide antibodies but not opioid antagonists block the activity. Brain Behav Immun. 2008 Aug;22(6):824-32. PMID: 18374539.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E6256

    Epothilone A

    Microtubule depolymerization inhibitor.

    ≥95%
  • B6856

    5-Bromo-2′-Deoxyuridine

    Nucleoside (thymidine) analog.

    ≥98%
  • N5767

    Norethindrone

    Steroid hormone, contraceptive; PR agonist.

    ≥98%
  • U6858

    Urocortin II, mouse

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • G733400

    GSK-2578215A

    Selective inhibitor of LRRK2.

    ≥98%
  • L0108

    Lacidipine

    Calcium channel blocker.

    ≥98%
  • F4482

    Fluvastatin Sodium

    Statin; HMG-CoA reductase inhibitor, potential ...

    ≥98%
  • T2817

    Theophylline

    Methylxanthine; PDE inhibitor, A1/2 adenosine a...

    ≥98%
  • B1652

    Benzo[a]pyrene

    Polycyclic aromatic hydrocarbon (PAH) found in ...

    ≥98%
  • A985120

    AZD-0156

    Inhibitor of ATM.

    ≥98%
  • B0110

    Baclofen

    GABA derivative; GABA-B agonist.

    ≥98%
  • P0005

    Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat

    Endogenous peptide, involved in paracrine and a...

    ≥95%
  • M0172

    Mastoparan

    Antimicrobial peptide found in Vespula lewisii,...

    ≥95%
  • H9620

    7-Hydroxyaristolochic Acid A

    Derivative of aristolochic acid found in Asarum...

    ≥95%
  • A464768

    Altertoxin 1

    Mycotoxin contaminant in food and feed.

    ≥97%
  • A0970

    Adrenocorticotropic Hormone (18-39), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • B5648

    Bombesin

    GRP analog, found in Bombina; bombesin and GRP ...

    ≥95%
  • V1854

    Venlafaxine Hydrochloride

    SERT, NET, MAO inhibitor.

    ≥98%
  • A9818

    Azelastine Hydrochloride

    TRPV1 agonist, histamine H1 antagonist.

    ≥98%
  • F1669

    Ferulic Acid

    Hydroxycinnamic acid found in various plant sou...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only