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C-82

C-82

Product ID C000082
Cas No. 1422253-37-9
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $104.80 In stock
5 mg $204.00 In stock
10 mg $347.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

C-82 is an active metabolite of PRI-724 and is an inhibitor of beta-catenin. Endometriotic cyst stromal cells treated with C-82 in vitro showed inhibited cell growth, cell migration, and fibrosis.

Product Info

Cas No.

1422253-37-9

Purity

≥99%

Formula

C33H34N6O4

Formula Wt.

578.67

IUPAC Name

(6S,9S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide

Synonym

C 82, C82

Appearance

White crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

C000082 Info Sheet PDF

References

Hirakawa T, Nasu K, Miyabe S, et al. beta-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis. Sci Rep. 2019 Dec 27;9(1):20056. PMID: 31882904

Lafyatis R, Mantero J, Gordon J, et al. Inhibition of beta-catenin signaling in the skin rescues cutaneous adipogenesis in systemic sclerosis: a randomized, double-blind, placebo-controlled trial of C-82. J Invest Dermatol. 2017 Dec;137(12):2473-2483. PMID: 28807667

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
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