Description
C-82 is an active metabolite of PRI-724 adn is an inhibitor of beta-catenin. Endometriotic cyst stromal cells treated with C-82 in vitro showed inhibited cell growth, cell migration, and fibrosis.
C-82
Product ID C000082
Cas No. 1422253-37-9
Purity ≥99%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 1422253-37-9 |
|---|---|
| Purity | ≥99% |
| Formula | C33H34N6O4 |
| Formula Wt. | 578.67 |
| IUPAC Name | (6S,9S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-2,9-dimethyl-4,7-dioxo-8-(quinolin-8-ylmethyl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide |
| Synonym | C 82, C82 |
| Appearance | White crystalline powder |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Hirakawa T, Nasu K, Miyabe S, et al. beta-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis. Sci Rep. 2019 Dec 27;9(1):20056. PMID: 31882904
Lafyatis R, Mantero J, Gordon J, et al. Inhibition of beta-catenin signaling in the skin rescues cutaneous adipogenesis in systemic sclerosis: a randomized, double-blind, placebo-controlled trial of C-82. J Invest Dermatol. 2017 Dec;137(12):2473-2483. PMID: 28807667