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Capecitabine

Capecitabine

Product ID C0162
Cas No. 154361-50-9
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $61.40 In stock
250 mg $102.00 In stock
1 g $306.20 In stock
5 g $980.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Capecitabine is an antifolate anticancer chemotherapeutic that acts as a prodrug of 5-fluorouracil (5-FU), a fluoropyrimidine carbamate that inhibits thymidylate synthase. Capecitabine is converted to 5-FU by thymidine phosphorylase in vivo. Capecitabine displays varying efficacy in the treatment of colorectal, metastatic breast, prostate, ovarian, and pancreatic cancers.

Product Info

Cas No.

154361-50-9

Purity

≥98%

Formula

C15H22FN3O6

Formula Wt.

359.35

Chemical Name

pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate

IUPAC Name

pentyl N-[1-[(2R,3R,4S,5R)-3, 4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate

Melting Point

110-121°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C0162 MSDS PDF

Info Sheet

C0162 Info Sheet PDF

References

Wilson PM, Fazzone W, LaBonte MJ, et al. Novel opportunities for thymidylate metabolism as a therapeutic target. Mol Cancer Ther. 2008 Sep;7(9):3029-37. PMID: 18790783.

Walko CM, Lindley C. Capecitabine: a review. Clin Ther. 2005 Jan;27(1):23-44. PMID: 15763604.

Ishikawa T, Utoh M, Sawada N, et al. Tumor selective delivery of 5-fluorouracil by capecitabine, a new oral fluoropyrimidine carbamate, in human cancer xenografts. Biochem Pharmacol. 1998 Apr 1;55(7):1091-7. PMID: 9605432.

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