Description
Carbinoxamine maleate is the maleic acid salt of carbinoxamine. It is well know as a histamine H1-antagonist, and anticholinergic agent. It has also been shown to inhibit infection by influenza A and B viruses in mice.
Carbinoxamine Maleate
Product ID C022692
Cas No. 3505-38-2
Purity ≥98%
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Product Info
| Cas No. | 3505-38-2 |
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| Purity | ≥98% |
| Formula | C20H23ClN2O5 |
| Formula Wt. | 406.86 |
| Chemical Name | 2-[(4-Clorophenyl)-2-pyridinylmethoxy]-N,N-dimethylethanamine maleate |
| IUPAC Name | (Z)-but-2-enedioic acid;2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine |
| Synonym | Carbinoxamine maleate salt; Lergefin; Ciberon |
| Melting Point | 116-118°C |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Deng Y, Wang T, Li J, et at. Studies on the in vitro ion exchange kinetics and thermodynamics and in vivo pharmocokinetics of the carbinoxamine-resin complex. Int J Pharm. 2020 Oct 15;588:119779. PMID: 32805380.
El-Masry S, El-Morsi R. Simple HPLC method for quantitative determination of carbinoxamine in human plasma: application in pharmacokinetic studies and therapeutic drug monitoring. Drug Res (Stuttg). 2019 Jun;69(6):342-347. PMID: 30658353.
Xu W, Xia S, Pu J, et al. The antihistamine drugs carbinoxamine maleate and chlorpheniramine maleate exhibit potent antiviral activity against a broad spectrum of influenza viruses. Front Microbiol. 2018 Nov 6;9:2643. PMID: 30459739.