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Cerulenin

Cerulenin

Product ID C1869
Cas No. 17397-89-6
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $99.90 In stock
5 mg $260.00 In stock
10 mg $433.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cerulenin is an inhibitor of fatty acid synthase found in Cephalosporium. Cerulenin exhibits antibiotic, antifungal, and anticancer chemotherapeutic activities. In cellular and animal models of colon cancer, cerulenin induces apoptosis and cellular death and decreases tumor growth. Cerulenin may also inhibit insulin secretion.

Product Info

Cas No.

17397-89-6

Purity

≥98%

Formula

C12H17NO3

Formula Wt.

223.27

Chemical Name

(2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadienyl]oxirane- carboxamide

IUPAC Name

(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide

Synonym

Helicocerin

Melting Point

93-94°C

Solubility

Soluble in ethanol, acetone, or benzene. Slightly soluble in water.

Appearance

White powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

C1869 MSDS PDF

Info Sheet

C1869 Info Sheet PDF

References

Straub SG, Sharp GW. Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev. 2007 Feb;23(2):146-51. PMID: 16705622.

Price AC, Choi KH, Heath RJ, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9. PMID: 11050088.

Huang P, Zhu S, Lu S, et al. Cerulenin inhibits growth of human colonic carcinoma in nude mice. Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):435-8. PMID: 11866947.

Custom Order

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