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Cisatracurium Besylate

Cisatracurium Besylate

Product ID C3472
Cas No. 96946-42-8
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $97.70 Please Inquire
25 mg $150.90 Please Inquire
100 mg $503.40 Please Inquire
500 mg $1,416.80 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cisatracurium is a non-depolarizing neuromuscular junction (NMJ) blocker; it binds the α-δ interface of postsynaptic nicotinic acetylcholine receptors (nAChRs). Cisatracurium acts as a skeletal muscle relaxant and is an isomer of parent compound atracurium. Cisatracurium also suppresses atrial fibrillation and prevents action potential shortening in vivo, indicating additional inhibition of M2 muscarinic acetylcholine receptors (mAChRs) in the atrium.

Product Info

Cas No.

96946-42-8

Purity

≥99%

Formula

C53H72N2O12 • 2C6H5O3S

Formula Wt.

1243.48

IUPAC Name

benzenesulfonate;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6, 7-dimethoxy-2-methyl-3, 4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1S,2S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3, 4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate

Appearance

Slightly yellow powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

C3472 MSDS PDF

Info Sheet

C3472 Info Sheet PDF

References

Liu M, Dilger JP. Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. PMID: 18633030.

Patterson E, Scherlag BJ, Zhou J, et al. Antifibrillatory actions of cisatracurium: an atrial specific M2 receptor antagonist. J Cardiovasc Electrophysiol. 2008 Aug;19(8):861-8. PMID: 18363689.

Dilger JP, Vidal AM, Liu M, et al. Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists. Anesthesiology. 2007 Jun;106(6):1186-95. PMID: 17525594.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

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