Description
Closantel is an anti-parasitic/anti-helminthic compound that inhibits chitinase OvCHT1. Closantel also acts as a protonophore, inhibiting nematode development.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Closantel is an anti-parasitic/anti-helminthic compound that inhibits chitinase OvCHT1. Closantel also acts as a protonophore, inhibiting nematode development.
| Cas No. | 61438-64-0 |
|---|---|
| Purity | ≥98% |
| Formula | C22H14Cl2I2N2O2Na |
| Formula Wt. | 686.06 |
| Chemical Name | N-[5-Chloro-4-[(4-chlorophenyl)cyanomethyl]-2- methylphenyl]-2-hydroxy-3,5-di-iodobenzamide |
| IUPAC Name | sodium;2-[[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]carbamoyl]-4,6-diiodophenolate |
| Synonym | Flukiver, Seponver |
| Melting Point | 217.8°C |
| Solubility | Insoluble in water. |
| Appearance | White to yellowish Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gooyit M, Tricoche N, Lustigman S, et al. Dual Protonophore-Chitinase Inhibitors Dramatically Affect O. volvulus Molting. J Med Chem. 2014 Jun 20. [Epub ahead of print]. PMID: 24918716.
Effective against gram-positive pathogens
Peptide, urocortin II analog; CRFR2 agonist.
Organosulfur found in garlic; Microtubule polym...
Endogenous glycosaminoglycan that is produced b...
Reduces production of thyroid hormones
Aminoglycoside; protein translation inhibitor, ...
Thienylbutyl ITC analog.
Quinazolinone; mitochondrial division inhibitor...
Aromatase inhibitor.
Oligodendrocyte antigen used to induce EAE.
Metabolite of clofibrate; PPARα agonist.
Polyketide; CRM1 inhibitor.
Endogenous pyrimidine base required for product...
2-methyl-1,4-naphthoquinone derivative
PDE and adenosine deaminase inhibitor.
Cembranoid found in Sarcophyton.
Statin; HMG-CoA reductase inhibitor.
Selective inhibitor of c-Met.
MET inhibitor.