Description
CREBtide is a synthetic spliced variant of C-terminal response element binding protein CREB. CREBtide is a substrate of protein kinase D1 (PKD1) and PKA.
CREBtide
Product ID C6916
Cas No. 149155-45-3
Purity ≥95%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 149155-45-3 |
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| Purity | ≥95% |
| Formula | C73H127N29O18 |
| Formula Wt. | 1699.01 |
| IUPAC Name | (4S)-5-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-4-(diaminomethylideneamino)butyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoic acid |
| Solubility | Soluble in water. |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| Info Sheet |
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References
Rybin VO, Guo J, Harleton E, et al. Regulatory domain determinants that control PKD1 activity. J Biol Chem. 2012 Jun 29;287(27):22609-15. PMID: 22582392.
Colbran JL, Roach PJ, Fiol CJ, et al. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide. Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1277-82. PMID: 1338414.