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Cytochalasin C is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin C inhibits motility of spermatozoa in vitro. This compound also increases transcription of TGF-β, collagenase, fibronectin, and procollagens 1 and 2 in vitro.
| Cas No. | 22144-76-9 |
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| Purity | ≥98%, TLC |
| Formula | C30H37NO6 |
| Formula Wt. | 507.62 |
| IUPAC Name | (16-benzyl-5,12-dihydroxy-5,7,13,14-tetramethyl-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9,13-trien-2-yl) acetate |
| Melting Point | 260°C (dec) |
| Solubility | Dichloromethane , Ethyl acetate |
| Appearance | White Powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Varedi M, Ghahary A, Scott PG, et al. Cytoskeleton regulates expression of genes for transforming growth factor-beta 1 and extracellular matrix proteins in dermal fibroblasts. J Cell Physiol. 1997 Aug;172(2):192-9. PMID: 9258340.
Glinsukon T, Sinlapanapaporn S, Chulasamaya M. Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro. Res Commun Chem Pathol Pharmacol. 1986 Feb;51(2):265-8. PMID: 3961270.