• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Cytochalasin D

Cytochalasin D

Product ID C9881
Cas No. 22144-77-0
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $236.40 In stock
5 mg $976.60 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Cytochalasin D is a mycotoxin actin polymerization inhibitor initially produced by species of Aspergillus. Cytochalasin D exhibits anti-angiogenic and pro-oxidative activities. In endothelial cells, cytochalasin D inhibits FGF- and VEGF-induced angiogenesis. In other cellular models, cytochalasin D increases production of ROS and activity of NADPH oxidase. Additionally, this compound increases levels of PPARγ, lipoprotein lipase, and FABP4, controlling adipogenesis in stem cells through its effects on cytoskeletal tension.

Product Info

Cas No.

22144-77-0

Purity

≥98%

Formula

C30H37NO6

Formula Wt.

507.62

IUPAC Name

[(1R,2R,3E,5R,7S,9E,11R,12S,14S,15R,16S)-16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-6,18-dioxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl] acetate

Melting Point

255°C (dec)

Appearance

White Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

C9881 MSDS PDF

Info Sheet

C9881 Info Sheet PDF

References

Wilkins JR, Pike DB, Gibson CC, et al. Differential effects of cyclic stretch on bFGF- and VEGF-induced sprouting angiogenesis. Biotechnol Prog. 2014 Feb 14. [Epub ahead of print]. PMID: 24574264.

Choy JS, Lu X, Yang J, et al. Endothelial actin depolymerization mediates NADPH oxidase-superoxide production during flow reversal. Am J Physiol Heart Circ Physiol. 2014 Jan 1;306(1):H69-77. PMID: 24186098.

Schiller ZA, Schiele NR, Sims JK, et al. Adipogenesis of adipose-derived stem cells may be regulated via the cytoskeleton at physiological oxygen levels in vitro. Stem Cell Res Ther. 2013 Jul 9;4(4):79. PMID: 23838354.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S8013

    [Tyr8]-Substance P

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • P6852

    Propafenone Hydrochloride

    β-adrenergic antagonist, Kv1.4 and K2P2 K+ cha...

    ≥98%
  • D3228

    Dihydromyristicin

    Found in parsley.

    ≥98%
  • C000082

    C-82

    beta-catenin inhibitor

    ≥99%
  • F3209

    Fibronectin-Binding Protein

    Peptide, binds fibronectin.

    ≥95%
  • A0802

    Acarbose

    α-glucosidase inhibitor.

    ≥98%
  • S1060

    Small Cardioactive Peptide A

    Peptide found in molluscs, cardiomodulator.

    ≥95%
  • B6807

    [Des-Arg9]-Bradykinin

    Natriuretic, vasodilatory peptide, bradykinin a...

    ≥95%
  • C4534

    Clindamycin Palmitate Hydrochloride

    Lincosamide; ribosomal translocation and protei...

    ≥98%
  • D1694

    Dexamethasone Acetate Monohydrate

    Steroid; glucocorticoid agonist.

    ≥98%
  • R3449

    Rimonabant Hydrochloride

    CB1 inverse agonist.

    ≥98%
  • T165131

    Tedizolid

    Effective against gram-positive pathogens

    ≥98%
  • P3269

    Piroxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • A044176

    Abemaciclib

    CDK inhibitor.

    ≥98%
  • C5782

    Coumarin

    Benzopyrone found in various plants, precursor ...

    ≥98%
  • T6811

    Tranexamic Acid

    Plasminogen inhibitor.

    ≥98%
  • P6959

    Prothionamide

    Nicotinic acid derivative; InhA inhibitor.

    ≥98%
  • B8075

    4-tert-Butyl-5-Methoxy-1,2-quinone

    BHA derivative.

    ≥95%
  • T1644

    Telmisartan

    AT-II antagonist, PPARγ/δ modulator.

    ≥98%
  • D0004

    Dabrafenib

    B-Raf and c-Raf inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only