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Luciferins are light-emitting heterocyclic compounds commonly used in biochemistry. Luciferin is the natural ligand for the enzyme luciferase, which oxidizes the substrate, emitting energy in the form of light in the process. Firefly luciferase requires ATP for its reaction, emitting a greenish-yellow luminescence at a peak wavelength of approximately 530 nm. The free acid form of luciferin requires addition of a dilute base such as NaOH or KOH to dissolve in water.
| Cas No. | 2591-17-5 |
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| Purity | ≥98% |
| Formula | C11H8N2O3S2 |
| Formula Wt. | 280.32 |
| Chemical Name | (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid |
| IUPAC Name | (2Z,4S)-2-(6-oxo-1,3-benzothiazol-2-ylidene)-1, 3-thiazolidine-4-carboxylic acid |
| Synonym | D(-)-Luciferin |
| Solubility | Insoluble in water. Soluble in methanol. |
| Appearance | White to off white powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Hastings JW. Chemistries and colors of bioluminescent reactions: a review. Gene 1996;173(1 Spec No):5–11. PMID: 8707056.
Green A, McElroy WD. Function of adenosine triphosphate in the activation of luciferin. Arch. Biochem. Biophys. 1956 Oct;64(2):257–71. PMID: 13363432.