Description
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
| Cas No. | 4342-03-4 |
|---|---|
| Purity | ≥98% |
| Formula | C6H10N6O |
| Formula Wt. | 182.18 |
| Chemical Name | 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4- carboxamide |
| IUPAC Name | (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
| Synonym | Dacatic, DTIC-Dome, Deticene |
| Melting Point | 205°C |
| Solubility | Slightly soluble in water and alcohol. |
| Appearance | Light pink powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gallamini A, Di Raimondo F, La Nasa G, et al. Standard therapies versus novel therapies in Hodgkin lymphoma. Immunol Lett. 2013 Sep-Oct;155(1-2):56-9. PMID: 24140162.
Koprowska K, Czyż M. Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities. Postepy Hig Med Dosw (Online). 2011 Nov 23;65:734-51. PMID: 22173438.
GHS-R1a agonist, γ-secretase inhibitor.
MDM2 inhibitor.
Jumonji histone demethylase inhibitor.
Terpene alcohol found in spearmint oil; TRPV3 a...
Semi-synthetic diterpene originally found in Ta...
NSAID; TRPA1 agonist, COX-2 inhibitor.
Furanocoumarin found in Psoralea coryfolia, DNA...
β-adrenergic agonist.
BRD2/3/4 inhibitor.
Dynamin inhibitor.
BHA derivative, antioxidative food and cosmetic...
Glucocorticoid
Mycotoxin produced by Alternaria; oxidative pho...
Alkaloid compound found in Corydalis.
Rifampicin derivative; DNA-dependent RNA polyme...
Actinomycin derivative used to study apoptosis ...
Endogenous peptide, involved in stress signalin...
Neuroactive mycotoxin produced by Penicillum an...
Phenothiazine derivative; D1/2 and 5-HT1A/2A an...