Description
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dacarbazine is an alkylator that attaches alkyl groups to purine bases on DNA; it exhibits anticancer chemotherapeutic activity. Dacarbazine is clinically used to treat various forms of cancer.
| Cas No. | 4342-03-4 |
|---|---|
| Purity | ≥98% |
| Formula | C6H10N6O |
| Formula Wt. | 182.18 |
| Chemical Name | 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4- carboxamide |
| IUPAC Name | (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide |
| Synonym | Dacatic, DTIC-Dome, Deticene |
| Melting Point | 205°C |
| Solubility | Slightly soluble in water and alcohol. |
| Appearance | Light pink powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Gallamini A, Di Raimondo F, La Nasa G, et al. Standard therapies versus novel therapies in Hodgkin lymphoma. Immunol Lett. 2013 Sep-Oct;155(1-2):56-9. PMID: 24140162.
Koprowska K, Czyż M. Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities. Postepy Hig Med Dosw (Online). 2011 Nov 23;65:734-51. PMID: 22173438.
Mineralocorticoid antagonist.
Peptide, derivative of AT I, cleavage product o...
HEXIM1 activator.
Semi-synthetic vinca alkaloid from Catharanthus...
Recombinant BNP, cardiomodulatory peptide; NPR-...
Isoflavone, phytoestrogen found in soy; ER agon...
Endogenous steroid hormone, estradiol metabolit...
Caspase 9 substrate.
VEGFR1/2/3, TIE2, PDGFRβ, FGFR1, c-Kit, RET, B...
Endogenous peptide hormone, GLP-1 fragment, inv...
Polyketide; DNMT 1 inhibitor, RNA synthesis inh...
1,8-Diaza-anthracene-tetrone; JNK and ERK5 inhi...
Labdane diterpene found in Andrographolis; cNOS...
RAD51 inhibitor.
FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...
Macrolide; protein translation inhibitor, mamma...
Triterpene saponin found in Bupleurum.
Coumarin; VKORC1 inhibitor.
Peptide, used as control to measure RGDS peptid...
NSAID; COX-1/2 inhibitor.