Description
Dapagliflozin is an SGLT2 inhibitor.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dapagliflozin is an SGLT2 inhibitor.
| Cas No. | 461432-26-8 |
|---|---|
| Purity | ≥98% |
| Formula | C21H25ClO6 |
| Formula Wt. | 408.88 |
| IUPAC Name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
| Synonym | BMS-512148 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ogutveren M, Satiroglu O, Ozden Z, et al. Cardioprotective effects of dapagliflozin and trimetazidine on doxorubicin-induced cardiotoxicity in streptozocin-induced type 1 diabetic rats via endoplasmic reticulum stress. J Clin Med. 2025 Feb 16;14(4):1315. PMID: 40004844.
Xiong S, Huang L, Liu H, et al. Dapagliflozin exerts anti-apoptotic effects by mitigating macrophage polarization via modulation of the phosphoinositide 3-kinase/protein kinase B sigmaling pathway. World J Diabetes. 2025 Feb 15;16(2):97287. PMID: 39959262.
Londzin P, Zych M, Janas A, et al. Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozocin in rats. Biomed Pharmacother. 2025 Mar:184:117912. PMID: 39955854.
Hirose T, Takagi H, Kuno M, et al. Dapagliflozin increased pancreatic beta cell proliferation and insulinogenic index in mice fed a high-fat and high-sodium chloride diet. Biochem Biophys Res Commun. 2025 Feb 16:749:151364. PMID: 39855047.
Liu Y, Bai H, Guan H, et al. Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome. Gynecol Endocrinol. 2025 Dec;41(1):2454432. PMID: 39826530.
FAK inhibitor.
Long chain acylcarnitine involved in fatty acid...
GABA derivative; GABA-B agonist.
Xanthine derivative; adenosine A2 antagonist, P...
Recombinant HIV-1 antigen fragment.
Neuroactive mycotoxin produced by Penicillum an...
Mycotoxin produced by species of Aspergillus; D...
Triazole; 14-α demethylase inhibitor.
Topoisomerase II inhibitor, RPA modulator.
Oltipraz analog, salivary gland secretion enhan...
Steroidal saponin found in Tribulus, Trigonella...
Naturally produced ITC, sulfonyl analog of sulf...
Neuromodulator, biomarker
Wip1 inhibitor.
Alkaloid compound found in Corydalis.
Antimicrobial peptide found in Vespula lewisii,...
Selective estrogen receptor modulator.
Pyrrolidone; NMDA and mGluR5 agonist, N-type an...
Antineoplastic immunomodulator.
Triterpene saponin found in species of Panax.