Description
Dapagliflozin is an SGLT2 inhibitor.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dapagliflozin is an SGLT2 inhibitor.
| Cas No. | 461432-26-8 |
|---|---|
| Purity | ≥98% |
| Formula | C21H25ClO6 |
| Formula Wt. | 408.88 |
| IUPAC Name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
| Synonym | BMS-512148 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ogutveren M, Satiroglu O, Ozden Z, et al. Cardioprotective effects of dapagliflozin and trimetazidine on doxorubicin-induced cardiotoxicity in streptozocin-induced type 1 diabetic rats via endoplasmic reticulum stress. J Clin Med. 2025 Feb 16;14(4):1315. PMID: 40004844.
Xiong S, Huang L, Liu H, et al. Dapagliflozin exerts anti-apoptotic effects by mitigating macrophage polarization via modulation of the phosphoinositide 3-kinase/protein kinase B sigmaling pathway. World J Diabetes. 2025 Feb 15;16(2):97287. PMID: 39959262.
Londzin P, Zych M, Janas A, et al. Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozocin in rats. Biomed Pharmacother. 2025 Mar:184:117912. PMID: 39955854.
Hirose T, Takagi H, Kuno M, et al. Dapagliflozin increased pancreatic beta cell proliferation and insulinogenic index in mice fed a high-fat and high-sodium chloride diet. Biochem Biophys Res Commun. 2025 Feb 16:749:151364. PMID: 39855047.
Liu Y, Bai H, Guan H, et al. Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome. Gynecol Endocrinol. 2025 Dec;41(1):2454432. PMID: 39826530.
Diterpene found in Anisomeles.
Endogenous calcitonin-family peptide, involved ...
Dihydroxyphenolic acid found in cruciferous veg...
Oligopeptide found in Actinomycetes; protease i...
Diterpene found in Taxus, used to synthesize ta...
Hydrophobic β-lactam; penicillin binding prote...
Sulfonamide; carbonic anhydrase inhibitor, volt...
Flavonol found in fruits and vegetables; COMT i...
Endogenous peptide hormone, counteracts insulin...
Alkaline phosphatase substrate used to quantify...
Polyketide; CRM1 inhibitor.
Chaetocin is naturally produced by Chaetomium s...
p53 inhibitor
Peptide found in molluscs, cardiomodulator.
Benzimidazole; microtubule polymerization inhib...
Alkaloid originally found in species of Aconitu...
Caffeic acid ester found in Melissa, Salvia, an...
Diterpene alkaloid found in Lagochilus.
Isoquinoline alkaloid found in Corydalis, Phell...
Furanolactone found in citrus fruits.