Description
Dapagliflozin is an SGLT2 inhibitor.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Dapagliflozin is an SGLT2 inhibitor.
| Cas No. | 461432-26-8 |
|---|---|
| Purity | ≥98% |
| Formula | C21H25ClO6 |
| Formula Wt. | 408.88 |
| IUPAC Name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol |
| Synonym | BMS-512148 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Ogutveren M, Satiroglu O, Ozden Z, et al. Cardioprotective effects of dapagliflozin and trimetazidine on doxorubicin-induced cardiotoxicity in streptozocin-induced type 1 diabetic rats via endoplasmic reticulum stress. J Clin Med. 2025 Feb 16;14(4):1315. PMID: 40004844.
Xiong S, Huang L, Liu H, et al. Dapagliflozin exerts anti-apoptotic effects by mitigating macrophage polarization via modulation of the phosphoinositide 3-kinase/protein kinase B sigmaling pathway. World J Diabetes. 2025 Feb 15;16(2):97287. PMID: 39959262.
Londzin P, Zych M, Janas A, et al. Effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors, dapagliflozin and canagliflozin, on the musculoskeletal system in an experimental model of diabetes induced by high-fat diet and streptozocin in rats. Biomed Pharmacother. 2025 Mar:184:117912. PMID: 39955854.
Hirose T, Takagi H, Kuno M, et al. Dapagliflozin increased pancreatic beta cell proliferation and insulinogenic index in mice fed a high-fat and high-sodium chloride diet. Biochem Biophys Res Commun. 2025 Feb 16:749:151364. PMID: 39855047.
Liu Y, Bai H, Guan H, et al. Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome. Gynecol Endocrinol. 2025 Dec;41(1):2454432. PMID: 39826530.
Polyanionic sulfated glycosaminoglycan, endogen...
Polyether cationic ionophore.
β2-adrenergic agonist.
Vitamin B, required for formation of NAD and NA...
KRAS inhibitor
Furanocoumarin found in Psoralea coryfolia, DNA...
Macrolide antibiotic; vacuolar H+ ATPase inhibi...
Topoisomerase II inhibitor, RPA modulator.
mTORC1 inhibitor.
NET and SERT inhibitor, NMDA antagonist.
Coccidiostat; dihydrofolate reductase inhibitor...
p110γ PI3K inhibitor.
β2-adrenergic agonist, BChE inhibitor.
Recombinant HCV antigen fragment.
Synthesis impurity
β1-adrenergic antagonist.
Non-nitrogen bisphosphonate; mitochondrial ATP/...
Carotenoid terpene pigment found in various pla...
Imidazole; 14-α demethylase inhibitor, potenti...
BRD binding agent, CDK1/2/5/9 inhibitor.