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AZD-2014

Product ID A9710
Cas No. 1009298-59-2
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $162.00 In stock
5 mg $355.60 In stock
10 mg $636.70 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

AZD-2014 is an inhibitor of mTORC1/2 that exhibits anticancer chemotherapeutic activity. AZD-2014 induces autophagy and inhibits growth without causing apoptosis in colorectal cancer cells. In animal models, AZD-2014 inhibits tumor growth of colorectal cancer xenografts.

Product Info

Cas No.

1009298-59-2

Purity

≥98%

Formula

C25H30N6O3

Formula Wt.

462.54

IUPAC Name

3-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-N-methylbenzamide

Synonym

Vistusertib

Solubility

DMSO 38 mg/mL (82.15 mM) Water Insoluble Ethanol Insoluble

Appearance

Yellow Powder

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

A9710 MSDS PDF

Info Sheet

A9710 Info Sheet PDF

Brochures

PI3K-Akt-mTORC Pathway Booklet

References

Huo HZ, Zhou ZY, Wang B, et al. Dramatic suppression of colorectal cancer cell growth by the dual mTORC1 and mTORC2 inhibitor AZD-2014. Biochem Biophys Res Commun. 2014 Jan 10;443(2):406-12. PMID: 24309100.

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