• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dasatinib

Dasatinib

Product ID D023721
Cas No. 302962-49-8
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $48.00 In stock
100 mg $89.00 In stock
250 mg $239.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dasatinib is an anticancer chemotherapeutic compound that inhibits Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Dasatinib is clinically used to treat chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL); in acute myelogenous leukemia (AML) cells, dasatinib induces myeloid differentiation and autophagy. Dasatinib also displays antiviral activity, preventing dengue virus infection through its inhibition of FYN kinase.

Product Info

Cas No.

302962-49-8

Purity

≥99%

Formula

C22H26ClN7O2S

Formula Wt.

488.01

IUPAC Name

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide

Synonym

BMS354825, BMS-354825, Sprycel

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D023721 MSDS PDF

Info Sheet

D023721 Info Sheet PDF

References

Xie N, Zhong L, Liu L, et al. Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells. Biochem Pharmacol. 2014 May 1;89(1):74-85. PMID: 24607273.

de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol. 2013 Jul;87(13):7367-81. PMID: 23616652.

Montero JC, Seoane S, Ocaña A, et al. Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. Clin Cancer Res. 2011 Sep 1;17(17):5546-52. PMID: 21670084.

Das J, Chen P, Norris D, et al. 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem. 2006 Nov 16;49(23):6819-32. PMID: 17154512.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B030962

    BAY-1251152

    Inhibitor of PTEFb/CDK9.

    ≥98%
  • T5769

    Toremifene Base

    SERM, androgen modulator.

    ≥98%
  • H9716

    (E,Z)-4-Hydroxytamoxifen

    Selective estrogen receptor modulator.

    ≥97%
  • S8046

    R-Sulforaphane, High Purity

    Naturally occuring isothiocyanate found in broc...

    ≥98%
  • C0369

    Cardiogenol C Hydrochloride

    Induces cardiomyogenic effects in pluripotent c...

    ≥98%
  • T1777

    S,S-(+)-Tetrandrine

    Benzylisoquinoline alkaloid originally found in...

    ≥98%
  • G3453

    20(S)-Ginsenoside Rh2

    Triterpene saponin found in Panax.

    ≥98%
  • R3584

    Rivaroxaban

    Oxazolidone derivative; Factor Xa inhibitor.

    ≥98%
  • C0121

    Caffeic Acid

    Hydroxycinnamic acid found in coffee, argan oil...

    ≥99%
  • T6811

    Tranexamic Acid

    Plasminogen inhibitor.

    ≥98%
  • C9808

    CZC-54252

    LRRK2 inhibitor.

    ≥98%
  • K1978

    Ketorolac Tromethamine

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • G4580

    Glucosamine Hydrochloride

    Endogenous amino sugar precursor required for p...

    ≥96%
  • G3351

    Ginkgolic Acid (17:1)

    Mixture of alkylphenols found in Ginkgo; HIV pr...

    ≥98%
  • N1822

    Nefazodone Hydrochloride

    5-HT2 antagonist, SERT and NET inhibitor, hERG ...

    ≥98%
  • A0402

    Abacavir Sulfate

    Nucleoside (guanosine) analog; RT, guanylyl cyc...

    ≥98%
  • G0106

    Gabapentin

    GABA analog; GABA potentiator, adenosine A1 ago...

    ≥98%
  • S680017

    SR-717 Lithium Salt

    STING agonist

    ≥98%
  • M4200

    MK-0752

    γ-Secretase inhibitor.

    ≥98%
  • R6052

    Recombinant Mycoplasma Pneumonia Antigen

    Pneumonia antigen

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2026 LKT Laboratories, All Rights Reserved - Products for research use only