• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Dasatinib

Dasatinib

Product ID D023721
Cas No. 302962-49-8
Purity ≥99%
Product Unit SizeCostQuantityStock
25 mg $47.80 In stock
100 mg $88.60 In stock
250 mg $238.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Dasatinib is an anticancer chemotherapeutic compound that inhibits Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Dasatinib is clinically used to treat chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL); in acute myelogenous leukemia (AML) cells, dasatinib induces myeloid differentiation and autophagy. Dasatinib also displays antiviral activity, preventing dengue virus infection through its inhibition of FYN kinase.

Product Info

Cas No.

302962-49-8

Purity

≥99%

Formula

C22H26ClN7O2S

Formula Wt.

488.01

IUPAC Name

N-(2-Chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide

Synonym

BMS354825, BMS-354825, Sprycel

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D023721 MSDS PDF

Info Sheet

D023721 Info Sheet PDF

References

Xie N, Zhong L, Liu L, et al. Autophagy contributes to dasatinib-induced myeloid differentiation of human acute myeloid leukemia cells. Biochem Pharmacol. 2014 May 1;89(1):74-85. PMID: 24607273.

de Wispelaere M, LaCroix AJ, Yang PL. The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol. 2013 Jul;87(13):7367-81. PMID: 23616652.

Montero JC, Seoane S, Ocaña A, et al. Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. Clin Cancer Res. 2011 Sep 1;17(17):5546-52. PMID: 21670084.

Das J, Chen P, Norris D, et al. 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem. 2006 Nov 16;49(23):6819-32. PMID: 17154512.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I7074

    Irsogladine Maleate

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • O4400

    Olanzapine

    AMPK activator, D1-4, 5-HT1A/2/3/6/7, M1-5 mACh...

    ≥99%
  • B030964

    BAY-1816032

    BUB1 inhibitor.

    ≥99%
  • P1955

    Pentagastrin

    Synthetic peptide, stimulates gastric acid secr...

    ≥95%
  • C0148

    Calcitonin, human

    Endogenous neuropeptide hormone, lowers extrace...

    ≥95%
  • C4417

    Clemizole

    TRPC5 activator, NS4B and histamine H1 inhibito...

    ≥98%
  • A0002

    A66

    p110α PI3K inhibitor.

    ≥98%
  • A0248

    BAM-12P

    Peptide, cleavage product of proenkephalin; κO...

    ≥95%
  • D3219

    Diflubenzuron

    Benzoylurea, insect growth regulator; chitin sy...

    ≥95%
  • G0096

    GAY

    Tripeptide, used to tag proteins.

    ≥95%
  • F4881

    Flumequine Sodium

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • N3474

    Nisoldipine

    Calcium channel blocker.

    ≥98%
  • K977545

    Kynurenic acid

    Endogenous NMDA receptor antagonist.

    ≥99%
  • P600006

    RP-6306

    PKMYT1 inhibitor

    ≥98%
  • K1677

    Ketoprofen

    NSAID; COX-1/2 and lactate dehydrogenase inhibi...

    ≥98%
  • O6805

    Orbifloxacin

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥99%
  • D509921

    DMXAA

    Mouse selective STING agonist.

    ≥99%
  • A8070

    Auraptene

    Monoterpene coumarin ether found in Citrus; PPA...

    ≥98%
  • P0278

    Patulin

    Mycotoxin produced by Penicillum and Aspergillu...

    ≥98%
  • T1028

    Paclitaxel, 8-Hydro-bicyclo(3.3.0)octane

    Synthesis impurity

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only