LKT Labs

Biochemicals for Life Science Research

[Des-Pro2]-Bradykinin

[Des-Pro2]-Bradykinin

Product ID B6808
Cas No. 80943-05-1
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $98.40 Please Inquire
10 mg $167.80 Please Inquire
25 mg $294.60 Please Inquire
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Cas No.

80943-05-1
Purity

≥95%
Formula

C45H66N14O10
Formula Wt.

963.12
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6808 MSDS PDF
Info Sheet

B6808 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • H9714

    L-5-Hydroxytryptophan

    Endogenous amino acid, precursor of 5-HT and me...

    ≥98%
  • T5060

    TMP-269

    HDAC inhibitor.

    ≥98%
  • V3251

    Vinorelbine Base

    Semi-synthetic vinca alkaloid found in Catharan...

    ≥90%
  • V9200

    VX-950

    NS3/4A serine protease inhibitor.

    ≥98%
  • G7240

    GSK-2830371

    Wip1 inhibitor.

    ≥98%
  • P0245

    Palmatine Chloride Hydrate

    Isoquinoline alkaloid found in Corydalis, Phell...

    ≥96%
  • A5315

    Deoxyandrographolide

    Labdane diterpene found in Andrographolis; cNOS...

    ≥98%
  • L589921

    Loxapine Succinate

    D2 and D4 dopamine receptor inhibitor.

    ≥99%
  • P2012

    PF-04217903

    Triazolopyrazine; c-MET inhibitor.

    ≥98%
  • R2400

    RG-108

    DNMT inhibitor.

    ≥98%
  • B1746

    Belinostat

    HDAC inhibitor.

    ≥98%
  • N1822

    Nefazodone Hydrochloride

    5-HT2 antagonist, SERT and NET inhibitor, hERG ...

    ≥98%
  • B1879

    Betamethasone Valerate

    Synthetic steroid hormone; glucocorticoid agoni...

    ≥98%
  • S8247

    Sulfasalazine

    Mesalazine derivative, sulfa drug; sepiapterin ...

    ≥98%
  • R3222

    Rifamycin SV Monosodium

    Ansamycin; bacterial DNA-dependent RNA polymera...

    ≥98%
  • D3329

    7,8-Dihydroxyflavone Hydrate

    TrkB agonist.

    ≥99%
  • N4974

    NMS-E628

    ALK and Ros1 inhibitor, Trk antagonist.

    ≥98%
  • S1612

    Sedanolide

    Phthalide found in celery seeds; COX-1, COX-2, ...

    ≥98%
  • P7158

    Protopine

    Isoquinoline alkaloid found in a variety of pla...

    ≥98%
  • P7034

    Prion Peptide (106-126), human

    Synthetic peptide fragment, prion protein analo...

    ≥95%