LKT Labs

Biochemicals for Life Science Research

[Des-Pro2]-Bradykinin

[Des-Pro2]-Bradykinin

Product ID B6808
Cas No. 80943-05-1
Purity ≥95%
Product Unit SizeCostQuantityStock
5 mg $98.00 Please Inquire
10 mg $168.00 Please Inquire
25 mg $295.00 Please Inquire
Bulk Quote

Quicklinks

Description

Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro, bradykinin decreases H2O2-induced senescence, increases activity of superoxide dismutase (SOD), and suppresses DNA damage, ROS production, and NADPH oxidase activity. Additionally, bradykinin increases expression of VEGF and promotes tube formation in prostate cancer cells.

Product Info

Cas No.

80943-05-1
Purity

≥95%
Formula

C45H66N14O10
Formula Wt.

963.12
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

B6808 MSDS PDF
Info Sheet

B6808 Info Sheet PDF

References

Mamenko M, Zaika O, Pochynyuk O. Direct regulation of ENaC by bradykinin in the distal nephron. Implications for renal sodium handling. Curr Opin Nephrol Hypertens. 2014 Mar;23(2):122-9. PMID: 24378775.

Yu HS, Wang SW, Chang AC, et al. Bradykinin promotes vascular endothelial growth factor expression and increases angiogenesis in human prostate cancer cells. Biochem Pharmacol. 2014 Jan 15;87(2):243-53. PMID: 24225154.

Dong R, Xu X, Li G, et al. Bradykinin inhibits oxidative stress-induced cardiomyocytes senescence via regulating redox state. PLoS One. 2013 Oct 25;8(10):e77034. PMID: 24204728.

Feher A, Cassuto J, Szabo A, et al. Increased tissue angiotensin-converting enzyme activity impairs bradykinin-induced dilation of coronary arterioles in obesity. Circ J. 2013;77(7):1867-76. PMID: 23603844.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S0072

    5S rRNA modificator

    Electrophile used in 2’-hydroxyl acylation of...

    ≥98%
  • S8146

    Sulindac Sulfone

    NSAID; COX-1/2 and PDE inhibitor.

    ≥98%
  • R0253

    Ranitidine Hydrochloride

    Histamine H2 inverse agonist.

    ≥98%
  • B4974

    BMS-777607

    MET and Ron inhibitor.

    ≥99%
  • G124084

    GDC-0973

    MEK1 inhibitor.

    ≥99%
  • T5968

    Torsemide

    Loop diuretic; NKCC symporter and HSP90 inhibit...

    ≥99%
  • A5281

    Angiotensin II (4-8), human

    Endogenous peptide fragment, involved in vasoco...

    ≥95%
  • P8168

    Puromycin Dihydrochloride

    Protein synthesis inhibitor, DPP2 and metallope...

    ≥98%
  • A5283

    [Sar1]-Angiotensin II

    Peptide, derivative of AT II, involved in vasoc...

    ≥95%
  • R3476

    RITA

    p53 activator.

    ≥98%
  • A1016

    S-Acetyl-L-glutathione

    Alters intracellular glutathione levels.

    ≥98%
  • C5260

    C-type Natriuretic Peptide (1-22), pig/human/rat

    Endogenous cardiomodulatory peptide; NPR-B agon...

    ≥95%
  • M9608

    Myclobutanil

    14-α demethylase inhibitor.

    ≥97%
  • P0245

    Palmatine Chloride Hydrate

    Isoquinoline alkaloid found in Corydalis, Phell...

    ≥96%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • S2792

    SGX-523

    MET inhibitor.

    ≥98%
  • S8144

    Sulfadoxine

    Sulfonamide; dihydropteroate synthase inhibitor...

    ≥98%
  • A9978

    Aztreonam

    β-lactam; penicillin binding protein inhibitor...

    ≥96%
  • B3345

    (−)-Bilobalide

    Sesquiterpene lactone found in Ginkgo; GABA-A a...

    ≥98%
  • F1853

    Fenofibrate

    Fibrate; PPARα agonist.

    ≥98%