Dexamethasone

Name: Dexamethasone
SKU: D1693
Availability: InStock

Product ID D1693

Cas No. 50-02-2

Purity ≥99%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration and maturation of macrophages. Dexamethasone may also display anti-asthma benefit as well, through the upregulation of PTEN expression. Additionally, dexamethasone is often used in combination with other chemotherapies in the treatment of multiple myeloma.

Product Info

Cas No.	50-02-2
Purity	≥99%
Formula	C₂₂H₂₉FO₅
Formula Wt.	392.46
Chemical Name	(11β,16α)-9-Fluoro-11,17,21-trihydro-16-methyl- pregna-1,4-diene-3,20-dione
IUPAC Name	(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11, 17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-3-one
Synonym	Decadron, Maxidex
Melting Point	223-233°C
Solubility	Soluble in DMF (25 mg/mL) and DMSO (25 mg/mL). Sparingly soluble in ethanol. Insoluble in water.
Appearance	White Crystalline Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	D1693 MSDS PDF
Info Sheet	D1693 Info Sheet PDF

References

Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Phone
This field is for validation purposes and should be left unchanged.

Dexamethasone

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Usnic Acid

Triptorelin Acetate

Bexarotene

Chlortetracycline Hydrochloride

SR1001

TGR5 Receptor Agonist

Candesartan

Plasminogen Activator Inhibitor 1

Tamoxifen Citrate

AZD5991

L-Thyroxine Sodium Pentahydrate

Sildenafil Citrate

7-Methyl-6-mercaptopurine

Foscarnet Sodium Hydrate

Bergenin

Vandetanib

Ghrelin, human

BAY-1895344

Sirtinol

Allopurinol

Footer